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EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling.
Elife. 2022 Nov 24;11:e76387. doi: 10.7554/eLife.76387.
Elife. 2022.
PMID: 36421765
Free PMC article.
A novel mutation in EROS (CYBC1) causes chronic granulomatous disease.
Mortimer PM, Nichols E, Thomas J, Shanbhag R, Singh N, Coomber EL, Malik TH, Pickering MC, Randzavola L, Rae W, Bhattad S, Thomas DC.
Mortimer PM, et al.
Clin Immunol. 2023 Oct;255:109761. doi: 10.1016/j.clim.2023.109761. Epub 2023 Sep 8.
Clin Immunol. 2023.
PMID: 37673227
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Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity.
Randzavola LO, Strege K, Juzans M, Asano Y, Stinchcombe JC, Gawden-Bone CM, Seaman MN, Kuijpers TW, Griffiths GM.
Randzavola LO, et al.
J Clin Invest. 2019 Dec 2;129(12):5600-5614. doi: 10.1172/JCI129388.
J Clin Invest. 2019.
PMID: 31710310
Free PMC article.
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Mitochondrial translation is required for sustained killing by cytotoxic T cells.
Lisci M, Barton PR, Randzavola LO, Ma CY, Marchingo JM, Cantrell DA, Paupe V, Prudent J, Stinchcombe JC, Griffiths GM.
Lisci M, et al. Among authors: randzavola lo.
Science. 2021 Oct 15;374(6565):eabe9977. doi: 10.1126/science.abe9977. Epub 2021 Oct 15.
Science. 2021.
PMID: 34648346
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Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis.
Stinchcombe JC, Randzavola LO, Angus KL, Mantell JM, Verkade P, Griffiths GM.
Stinchcombe JC, et al. Among authors: randzavola lo.
Curr Biol. 2015 Dec 21;25(24):3239-44. doi: 10.1016/j.cub.2015.10.028. Epub 2015 Dec 5.
Curr Biol. 2015.
PMID: 26670998
Free PMC article.
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