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Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity.
Sternes PR, Brett L, Phipps J, Ciccia F, Kenna T, de Guzman E, Zimmermann K, Morrison M, Holtmann G, Klingberg E, Mauro D, McIvor C, Forsblad-d'Elia H, Brown MA. Sternes PR, et al. Arthritis Res Ther. 2022 Jul 7;24(1):163. doi: 10.1186/s13075-022-02853-3. Arthritis Res Ther. 2022. PMID: 35794662 Free PMC article.
Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy upon microbiome composition.
Yin J, Sternes PR, Wang M, Song J, Morrison M, Li T, Zhou L, Wu X, He F, Zhu J, Brown MA, Xu H. Yin J, et al. Among authors: sternes pr. Ann Rheum Dis. 2020 Jan;79(1):132-140. doi: 10.1136/annrheumdis-2019-215763. Epub 2019 Oct 29. Ann Rheum Dis. 2020. PMID: 31662318
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