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Development of a quantitative semi-mechanistic model of Alzheimer's disease based on the amyloid/tau/neurodegeneration framework (the Q-ATN model).
Mazer NA, Hofmann C, Lott D, Gieschke R, Klein G, Boess F, Grimm HP, Kerchner GA, Baudler-Klein M, Smith J, Doody RS; Alzheimer's Disease Neuroimaging Initiative. Mazer NA, et al. Among authors: smith j. Alzheimers Dement. 2023 Jun;19(6):2287-2297. doi: 10.1002/alz.12877. Epub 2022 Dec 1. Alzheimers Dement. 2023. PMID: 36454709
Gantenerumab in Early Alzheimer's Disease. Reply.
Bateman RJ, Smith J, Doody RS; GRADUATE I and II Investigators and the Gantenerumab Study Group. Bateman RJ, et al. Among authors: smith j. N Engl J Med. 2024 Feb 29;390(9):867. doi: 10.1056/NEJMc2314291. N Engl J Med. 2024. PMID: 38416440 No abstract available.
Large multicenter randomized trials in autism: key insights gained from the balovaptan clinical development program.
Jacob S, Anagnostou E, Hollander E, Jou R, McNamara N, Sikich L, Tobe R, Murphy D, McCracken J, Ashford E, Chatham C, Clinch S, Smith J, Sanders K, Murtagh L, Noeldeke J, Veenstra-VanderWeele J. Jacob S, et al. Among authors: smith j. Mol Autism. 2022 Jun 11;13(1):25. doi: 10.1186/s13229-022-00505-6. Mol Autism. 2022. PMID: 35690870 Free PMC article.
Balovaptan vs Placebo for Social Communication in Childhood Autism Spectrum Disorder: A Randomized Clinical Trial.
Hollander E, Jacob S, Jou R, McNamara N, Sikich L, Tobe R, Smith J, Sanders K, Squassante L, Murtagh L, Gleissl T, Wandel C, Veenstra-VanderWeele J. Hollander E, et al. Among authors: smith j. JAMA Psychiatry. 2022 Aug 1;79(8):760-769. doi: 10.1001/jamapsychiatry.2022.1717. JAMA Psychiatry. 2022. PMID: 35793101 Free PMC article. Clinical Trial.
A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors.
Sohn SJ, Barrett K, Van Abbema A, Chang C, Kohli PB, Kanda H, Smith J, Lai Y, Zhou A, Zhang B, Yang W, Williams K, Macleod C, Hurley CA, Kulagowski JJ, Lewin-Koh N, Dengler HS, Johnson AR, Ghilardi N, Zak M, Liang J, Blair WS, Magnuson S, Wu LC. Sohn SJ, et al. Among authors: smith j. J Immunol. 2013 Sep 1;191(5):2205-16. doi: 10.4049/jimmunol.1202859. Epub 2013 Jul 26. J Immunol. 2013. PMID: 23894201 Free PMC article.
Efficacy and safety of balovaptan for socialisation and communication difficulties in autistic adults in North America and Europe: a phase 3, randomised, placebo-controlled trial.
Jacob S, Veenstra-VanderWeele J, Murphy D, McCracken J, Smith J, Sanders K, Meyenberg C, Wiese T, Deol-Bhullar G, Wandel C, Ashford E, Anagnostou E. Jacob S, et al. Among authors: smith j. Lancet Psychiatry. 2022 Mar;9(3):199-210. doi: 10.1016/S2215-0366(21)00429-6. Epub 2022 Feb 10. Lancet Psychiatry. 2022. PMID: 35151410 Clinical Trial.
Quantitative and Qualitative Exploration of Meaningful Change on the Vineland Adaptive Behavior Scales (Vineland™-II) in Children and Adolescents with Autism Without Intellectual Disability Following Participation in a Clinical Trial.
Clinch S, Hudgens S, Gibbons E, Willgoss T, Smith J, Polek E, Burbridge C. Clinch S, et al. Among authors: smith j. Patient Relat Outcome Meas. 2023 Nov 20;14:337-354. doi: 10.2147/PROM.S385542. eCollection 2023. Patient Relat Outcome Meas. 2023. PMID: 38027418 Free PMC article.
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