Grunseich C - Search Results

1

A common transcriptional mechanism involving R-loop and RNA abasic site regulates an enhancer RNA of APOE.

Watts JA, Grunseich C, Rodriguez Y, Liu Y, Li D, Burdick JT, Bruzel A, Crouch RJ, Mahley RW, Wilson SH, Cheung VG. Watts JA, et al. Among authors: grunseich c. Nucleic Acids Res. 2022 Nov 28;50(21):12497-12514. doi: 10.1093/nar/gkac1107. Nucleic Acids Res. 2022. PMID: 36453989 Free PMC article.

2

RNA-DNA differences are generated in human cells within seconds after RNA exits polymerase II.

Wang IX, Core LJ, Kwak H, Brady L, Bruzel A, McDaniel L, Richards AL, Wu M, Grunseich C, Lis JT, Cheung VG. Wang IX, et al. Among authors: grunseich c. Cell Rep. 2014 Mar 13;6(5):906-15. doi: 10.1016/j.celrep.2014.01.037. Epub 2014 Feb 20. Cell Rep. 2014. PMID: 24561252 Free PMC article.

3

RNA-DNA sequence differences in Saccharomyces cerevisiae.

Wang IX, Grunseich C, Chung YG, Kwak H, Ramrattan G, Zhu Z, Cheung VG. Wang IX, et al. Among authors: grunseich c. Genome Res. 2016 Nov;26(11):1544-1554. doi: 10.1101/gr.207878.116. Epub 2016 Sep 16. Genome Res. 2016. PMID: 27638543 Free PMC article.

4

Senataxin Mutation Reveals How R-Loops Promote Transcription by Blocking DNA Methylation at Gene Promoters.

Grunseich C, Wang IX, Watts JA, Burdick JT, Guber RD, Zhu Z, Bruzel A, Lanman T, Chen K, Schindler AB, Edwards N, Ray-Chaudhury A, Yao J, Lehky T, Piszczek G, Crain B, Fischbeck KH, Cheung VG. Grunseich C, et al. Mol Cell. 2018 Feb 1;69(3):426-437.e7. doi: 10.1016/j.molcel.2017.12.030. Epub 2018 Jan 27. Mol Cell. 2018. PMID: 29395064 Free PMC article.

5

cis Elements that Mediate RNA Polymerase II Pausing Regulate Human Gene Expression.

Watts JA, Burdick J, Daigneault J, Zhu Z, Grunseich C, Bruzel A, Cheung VG. Watts JA, et al. Among authors: grunseich c. Am J Hum Genet. 2019 Oct 3;105(4):677-688. doi: 10.1016/j.ajhg.2019.08.003. Epub 2019 Sep 5. Am J Hum Genet. 2019. PMID: 31495490 Free PMC article.

6

Clinical and Molecular Aspects of Senataxin Mutations in Amyotrophic Lateral Sclerosis 4.

Grunseich C, Patankar A, Amaya J, Watts JA, Li D, Ramirez P, Schindler AB, Fischbeck KH, Cheung VG. Grunseich C, et al. Ann Neurol. 2020 Apr;87(4):547-555. doi: 10.1002/ana.25681. Epub 2020 Jan 28. Ann Neurol. 2020. PMID: 31957062 Free PMC article.

7

RNA abasic sites in yeast and human cells.

Liu Y, Rodriguez Y, Ross RL, Zhao R, Watts JA, Grunseich C, Bruzel A, Li D, Burdick JT, Prasad R, Crouch RJ, Limbach PA, Wilson SH, Cheung VG. Liu Y, et al. Among authors: grunseich c. Proc Natl Acad Sci U S A. 2020 Aug 25;117(34):20689-20695. doi: 10.1073/pnas.2011511117. Epub 2020 Aug 11. Proc Natl Acad Sci U S A. 2020. PMID: 32788345 Free PMC article.

8

R-Loop Analysis by Dot-Blot.

Ramirez P, Crouch RJ, Cheung VG, Grunseich C. Ramirez P, et al. Among authors: grunseich c. J Vis Exp. 2021 Jan 22;(167):10.3791/62069. doi: 10.3791/62069. J Vis Exp. 2021. PMID: 33554969 Free PMC article.

9

Targeting the 5' untranslated region of SMN2 as a therapeutic strategy for spinal muscular atrophy.

Winkelsas AM, Grunseich C, Harmison GG, Chwalenia K, Rinaldi C, Hammond SM, Johnson K, Bowerman M, Arya S, Talbot K, Wood MJ, Fischbeck KH. Winkelsas AM, et al. Among authors: grunseich c. Mol Ther Nucleic Acids. 2021 Jan 5;23:731-742. doi: 10.1016/j.omtn.2020.12.027. eCollection 2021 Mar 5. Mol Ther Nucleic Acids. 2021. PMID: 33575118 Free PMC article.

10

Human proteins that interact with RNA/DNA hybrids.

Wang IX, Grunseich C, Fox J, Burdick J, Zhu Z, Ravazian N, Hafner M, Cheung VG. Wang IX, et al. Among authors: grunseich c. Genome Res. 2018 Sep;28(9):1405-1414. doi: 10.1101/gr.237362.118. Epub 2018 Aug 14. Genome Res. 2018. PMID: 30108179 Free PMC article.

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