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Insight into the mechanism of AML del(9q) progression: hnRNP K targets the myeloid master regulators CEBPA (C/EBPα) and SPI1 (PU.1).
Rahn K, Abdallah AT, Gan L, Herbrich S, Sonntag R, Benitez O, Malaney P, Zhang X, Rodriguez AG, Brottem J, Marx G, Brümmendorf TH, Ostareck DH, Ostareck-Lederer A, Crysandt M, Post SM, Naarmann-de Vries IS. Rahn K, et al. Among authors: malaney p. Biochim Biophys Acta Gene Regul Mech. 2024 Mar;1867(1):195004. doi: 10.1016/j.bbagrm.2023.195004. Epub 2023 Nov 25. Biochim Biophys Acta Gene Regul Mech. 2024. PMID: 38008244
Heterogeneous nuclear ribonucleoprotein K is overexpressed in acute myeloid leukemia and causes myeloproliferation in mice via altered Runx1 splicing.
Aitken MJL, Malaney P, Zhang X, Herbrich SM, Chan L, Benitez O, Rodriguez AG, Ma H, Jacamo R, Duan R, Link TM, Kornblau SM, Kanagal-Shamanna R, Bueso-Ramos CE, Post SM. Aitken MJL, et al. Among authors: malaney p. NAR Cancer. 2022 Dec 9;4(4):zcac039. doi: 10.1093/narcan/zcac039. eCollection 2022 Dec. NAR Cancer. 2022. PMID: 36518526 Free PMC article.
Creating accessibility in academic negotiations.
Kong JH, Vasquez CG, Agrawal S, Malaney P, Mikedis MM, Moffitt AB, von Diezmann L, Termini CM. Kong JH, et al. Among authors: malaney p. Trends Biochem Sci. 2023 Mar;48(3):203-210. doi: 10.1016/j.tibs.2022.10.004. Epub 2022 Dec 9. Trends Biochem Sci. 2023. PMID: 36504139
AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3-ITD acute myeloid leukemia.
Post SM, Ma H, Malaney P, Zhang X, Aitken MJL, Mak PY, Ruvolo VR, Yasuhiro T, Kozaki R, Chan LE, Ostermann LB, Konopleva M, Carter BZ, DiNardo C, Andreeff MD, Khoury JD, Ruvolo PP. Post SM, et al. Among authors: malaney p. Haematologica. 2022 Jun 1;107(6):1311-1322. doi: 10.3324/haematol.2021.278369. Haematologica. 2022. PMID: 34732043 Free PMC article.
Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas.
Gallardo M, Malaney P, Aitken MJL, Zhang X, Link TM, Shah V, Alybayev S, Wu MH, Pageon LR, Ma H, Jacamo R, Yu L, Xu-Monette ZY, Steinman H, Lee HJ, Sarbassov D, Rapado I, Barton MC, Martinez-Lopez J, Bueso-Ramos C, Young KH, Post SM. Gallardo M, et al. Among authors: malaney p. J Natl Cancer Inst. 2020 Jan 1;112(1):95-106. doi: 10.1093/jnci/djz078. J Natl Cancer Inst. 2020. PMID: 31077320 Free PMC article.
PTEN proteoforms in biology and disease.
Malaney P, Uversky VN, Davé V. Malaney P, et al. Cell Mol Life Sci. 2017 Aug;74(15):2783-2794. doi: 10.1007/s00018-017-2500-6. Epub 2017 Mar 13. Cell Mol Life Sci. 2017. PMID: 28289760 Free PMC article. Review.
20 results