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Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates.
Mandal M, Xiao L, Pan W, Scapin G, Li G, Tang H, Yang SW, Pan J, Root Y, de Jesus RK, Yang C, Prosise W, Dayananth P, Mirza A, Therien AG, Young K, Flattery A, Garlisi C, Zhang R, Chu D, Sheth P, Chu I, Wu J, Markgraf C, Kim HY, Painter R, Mayhood TW, DiNunzio E, Wyss DF, Buevich AV, Fischmann T, Pasternak A, Dong S, Hicks JD, Villafania A, Liang L, Murgolo N, Black T, Hagmann WK, Tata J, Parmee ER, Weber AE, Su J, Tang H. Mandal M, et al. Among authors: chu d, chu i. J Med Chem. 2022 Dec 22;65(24):16234-16251. doi: 10.1021/acs.jmedchem.2c00766. Epub 2022 Dec 7. J Med Chem. 2022. PMID: 36475645
Inhibition of Factor XIa Reduces the Frequency of Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits.
Wang X, Kurowski S, Wu W, Castriota GA, Zhou X, Chu L, Ellsworth KP, Chu D, Edmondson S, Ali A, Andre P, Seiffert D, Erion M, Gutstein DE, Chen Z. Wang X, et al. Among authors: chu d, chu l. J Pharmacol Exp Ther. 2017 Mar;360(3):476-483. doi: 10.1124/jpet.116.238600. Epub 2016 Dec 29. J Pharmacol Exp Ther. 2017. PMID: 28035007
Multi-interface Engineering of MXenes for Self-Powered Wearable Devices.
Liu C, Feng Z, Yin T, Wan T, Guan P, Li M, Hu L, Lin CH, Han Z, Xu H, Chen W, Wu T, Liu G, Zhou Y, Peng S, Wang C, Chu D. Liu C, et al. Among authors: chu d. Adv Mater. 2024 May 23:e2403791. doi: 10.1002/adma.202403791. Online ahead of print. Adv Mater. 2024. PMID: 38780429 Review.
2,532 results