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Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage.
Ferreira-Gonzalez S, Man TY, Esser H, Aird R, Kilpatrick AM, Rodrigo-Torres D, Younger N, Campana L, Gadd VL, Dwyer B, Aleksieva N, Boulter L, Macmillan MT, Wang Y, Mylonas KJ, Ferenbach DA, Kendall TJ, Lu WY, Acosta JC, Kurian D, O'Neill S, Oniscu GC, Banales JM, Krimpenfort PJ, Forbes SJ. Ferreira-Gonzalez S, et al. Among authors: aird r. Sci Transl Med. 2022 Dec 7;14(674):eabj4375. doi: 10.1126/scitranslmed.abj4375. Epub 2022 Dec 7. Sci Transl Med. 2022. PMID: 36475903
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease.
Hallett JM, Ferreira-Gonzalez S, Man TY, Kilpatrick AM, Esser H, Thirlwell K, Macmillan MT, Rodrigo-Torres D, Dwyer BJ, Gadd VL, Ashmore-Harris C, Lu WY, Thomson JP, Jansen MA, O'Duibhir E, Starkey Lewis PJ, Campana L, Aird RE, Bate TSR, Fraser AR, Campbell JDM, Oniscu GC, Hay DC, Callanan A, Forbes SJ. Hallett JM, et al. Among authors: aird re. Cell Stem Cell. 2022 Mar 3;29(3):355-371.e10. doi: 10.1016/j.stem.2022.02.006. Cell Stem Cell. 2022. PMID: 35245467 Free PMC article.
Alternatively activated macrophages promote resolution of necrosis following acute liver injury.
Starkey Lewis P, Campana L, Aleksieva N, Cartwright JA, Mackinnon A, O'Duibhir E, Kendall T, Vermeren M, Thomson A, Gadd V, Dwyer B, Aird R, Man TY, Rossi AG, Forrester L, Park BK, Forbes SJ. Starkey Lewis P, et al. Among authors: aird r. J Hepatol. 2020 Aug;73(2):349-360. doi: 10.1016/j.jhep.2020.02.031. Epub 2020 Mar 11. J Hepatol. 2020. PMID: 32169610 Free PMC article.
Pharmacological Activation of Nrf2 Enhances Functional Liver Regeneration.
Chan BKY, Elmasry M, Forootan SS, Russomanno G, Bunday TM, Zhang F, Brillant N, Starkey Lewis PJ, Aird R, Ricci E, Andrews TD, Sison-Young RL, Schofield AL, Fang Y, Lister A, Sharkey JW, Poptani H, Kitteringham NR, Forbes SJ, Malik HZ, Fenwick SW, Park BK, Goldring CE, Copple IM. Chan BKY, et al. Among authors: aird r. Hepatology. 2021 Aug;74(2):973-986. doi: 10.1002/hep.31859. Epub 2021 Jul 13. Hepatology. 2021. PMID: 33872408
Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
Hayward RL, Schornagel QC, Tente R, Macpherson JS, Aird RE, Guichard S, Habtemariam A, Sadler P, Jodrell DI. Hayward RL, et al. Among authors: aird re. Cancer Chemother Pharmacol. 2005 Jun;55(6):577-83. doi: 10.1007/s00280-004-0932-9. Epub 2005 Feb 22. Cancer Chemother Pharmacol. 2005. PMID: 15726367
126 results