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Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage.
Ferreira-Gonzalez S, Man TY, Esser H, Aird R, Kilpatrick AM, Rodrigo-Torres D, Younger N, Campana L, Gadd VL, Dwyer B, Aleksieva N, Boulter L, Macmillan MT, Wang Y, Mylonas KJ, Ferenbach DA, Kendall TJ, Lu WY, Acosta JC, Kurian D, O'Neill S, Oniscu GC, Banales JM, Krimpenfort PJ, Forbes SJ. Ferreira-Gonzalez S, et al. Among authors: ferenbach da. Sci Transl Med. 2022 Dec 7;14(674):eabj4375. doi: 10.1126/scitranslmed.abj4375. Epub 2022 Dec 7. Sci Transl Med. 2022. PMID: 36475903
Therapeutic Approaches to Aging.
O'Sullivan ED, Mylonas KJ, Ferenbach DA. O'Sullivan ED, et al. Among authors: ferenbach da. JAMA. 2019 Mar 5;321(9):901. doi: 10.1001/jama.2018.20550. JAMA. 2019. PMID: 30835302 No abstract available.
Cellular Senescence in the Kidney.
Docherty MH, O'Sullivan ED, Bonventre JV, Ferenbach DA. Docherty MH, et al. Among authors: ferenbach da. J Am Soc Nephrol. 2019 May;30(5):726-736. doi: 10.1681/ASN.2018121251. Epub 2019 Apr 18. J Am Soc Nephrol. 2019. PMID: 31000567 Free PMC article. Review.
Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis.
O'Sullivan ED, Mylonas KJ, Bell R, Carvalho C, Baird DP, Cairns C, Gallagher KM, Campbell R, Docherty M, Laird A, Henderson NC, Chandra T, Kirschner K, Conway B, Dihazi GH, Zeisberg M, Hughes J, Denby L, Dihazi H, Ferenbach DA. O'Sullivan ED, et al. Among authors: ferenbach da. JCI Insight. 2022 Nov 22;7(22):e154124. doi: 10.1172/jci.insight.154124. JCI Insight. 2022. PMID: 36509292 Free PMC article.
Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis.
O'Sullivan ED, Mylonas KJ, Xin C, Baird DP, Carvalho C, Docherty MH, Campbell R, Matchett KP, Waddell SH, Walker AD, Gallagher KM, Jia S, Leung S, Laird A, Wilflingseder J, Willi M, Reck M, Finnie S, Pisco A, Gordon-Keylock S, Medvinsky A, Boulter L, Henderson NC, Kirschner K, Chandra T, Conway BR, Hughes J, Denby L, Bonventre JV, Ferenbach DA. O'Sullivan ED, et al. Among authors: ferenbach da. Sci Transl Med. 2023 May 31;15(698):eabn0736. doi: 10.1126/scitranslmed.abn0736. Epub 2023 May 31. Sci Transl Med. 2023. PMID: 37256934 Free article.
35 results