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NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin.
Lipka E, Chadderdon AM, Harteg CC, Doherty MK, Simon ES, Domagala JM, Reyna DM, Hutchings KM, Gan X, White AD, Hartline CB, Harden EA, Keith KA, Prichard MN, James SH, Cardin RD, Bernstein DI, Spencer JF, Tollefson AE, Wold WSM, Toth K. Lipka E, et al. Among authors: doherty mk. Mol Pharm. 2023 Jan 2;20(1):370-382. doi: 10.1021/acs.molpharmaceut.2c00668. Epub 2022 Dec 9. Mol Pharm. 2023. PMID: 36484496 Free PMC article.
Sequence analysis of Discoknowium, an A5 mycobacteriophage.
Carline KBR, Fleeharty MS, Fang L, Shijo M, Doherty MK, Riddick ZA, Royster MO, Stukes AR, Tchadi BV, Thomas AN, Williamson KE, Saha MS. Carline KBR, et al. Among authors: doherty mk. Microbiol Resour Announc. 2024 Jan 17;13(1):e0092023. doi: 10.1128/MRA.00920-23. Epub 2023 Dec 4. Microbiol Resour Announc. 2024. PMID: 38047653 Free PMC article.
CBL/CAP Is Essential for Mitochondria Respiration Complex I Assembly and Bioenergetics Efficiency in Muscle Cells.
Aye CC, Hammond DE, Rodriguez-Cuenca S, Doherty MK, Whitfield PD, Phelan MM, Yang C, Perez-Perez R, Li X, Diaz-Ramos A, Peddinti G, Oresic M, Vidal-Puig A, Zorzano A, Ugalde C, Mora S. Aye CC, et al. Among authors: doherty mk. Int J Mol Sci. 2023 Feb 8;24(4):3399. doi: 10.3390/ijms24043399. Int J Mol Sci. 2023. PMID: 36834818 Free PMC article.
Randomised, Phase II study of selumetinib, an oral inhibitor of MEK, in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer.
Doherty MK, Tam VC, McNamara MG, Jang R, Hedley D, Chen E, Dhani N, Tang P, Sim HW, O'Kane GM, DeLuca S, Wang L, Pedutem T, Knox JJ. Doherty MK, et al. Br J Cancer. 2022 Nov;127(8):1473-1478. doi: 10.1038/s41416-022-01903-6. Epub 2022 Jul 22. Br J Cancer. 2022. PMID: 35869145 Free PMC article. Clinical Trial.
73 results