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NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin.
Lipka E, Chadderdon AM, Harteg CC, Doherty MK, Simon ES, Domagala JM, Reyna DM, Hutchings KM, Gan X, White AD, Hartline CB, Harden EA, Keith KA, Prichard MN, James SH, Cardin RD, Bernstein DI, Spencer JF, Tollefson AE, Wold WSM, Toth K. Lipka E, et al. Among authors: prichard mn. Mol Pharm. 2023 Jan 2;20(1):370-382. doi: 10.1021/acs.molpharmaceut.2c00668. Epub 2022 Dec 9. Mol Pharm. 2023. PMID: 36484496 Free PMC article.
USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses.
Toth K, Spencer JF, Ying B, Tollefson AE, Hartline CB, Richard ET, Fan J, Lyu J, Kashemirov BA, Harteg C, Reyna D, Lipka E, Prichard MN, McKenna CE, Wold WSM. Toth K, et al. Among authors: prichard mn. Antiviral Res. 2018 May;153:1-9. doi: 10.1016/j.antiviral.2018.03.001. Epub 2018 Mar 3. Antiviral Res. 2018. PMID: 29510156 Free PMC article.
Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses.
Toth K, Hussein ITM, Tollefson AE, Ying B, Spencer JF, Eagar J, James SH, Prichard MN, Wold WSM, Bowlin TL. Toth K, et al. Among authors: prichard mn. Antimicrob Agents Chemother. 2020 Oct 20;64(11):e01299-20. doi: 10.1128/AAC.01299-20. Print 2020 Oct 20. Antimicrob Agents Chemother. 2020. PMID: 32816736 Free PMC article.
Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses.
Prichard MN, Williams JD, Komazin-Meredith G, Khan AR, Price NB, Jefferson GM, Harden EA, Hartline CB, Peet NP, Bowlin TL. Prichard MN, et al. Antimicrob Agents Chemother. 2013 Aug;57(8):3518-27. doi: 10.1128/AAC.00429-13. Epub 2013 May 13. Antimicrob Agents Chemother. 2013. PMID: 23669381 Free PMC article.
113 results