Holmes AP - Search Results

1

Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide.

O'Reilly M, Sommerfeld LC, O'Shea C, Broadway-Stringer S, Andaleeb S, Reyat JS, Kabir SN, Stastny D, Malinova A, Delbue D, Fortmueller L, Gehmlich K, Pavlovic D, Skryabin BV, Holmes AP, Kirchhof P, Fabritz L. O'Reilly M, et al. Among authors: holmes ap. Europace. 2023 Mar 30;25(3):1152-1161. doi: 10.1093/europace/euac218. Europace. 2023. PMID: 36504385 Free PMC article.

2

An automated system using spatial oversampling for optical mapping in murine atria. Development and validation with monophasic and transmembrane action potentials.

Yu TY, Syeda F, Holmes AP, Osborne B, Dehghani H, Brain KL, Kirchhof P, Fabritz L. Yu TY, et al. Among authors: holmes ap. Prog Biophys Mol Biol. 2014 Aug;115(2-3):340-8. doi: 10.1016/j.pbiomolbio.2014.07.012. Epub 2014 Aug 15. Prog Biophys Mol Biol. 2014. PMID: 25130572 Free PMC article.

3

Pitx2 Adjacent Noncoding RNA: A New, Long, Noncoding Kid on the 4q25 Block.

Holmes AP, Kirchhof P. Holmes AP, et al. Circ Arrhythm Electrophysiol. 2016 Jan;9(1):e003808. doi: 10.1161/CIRCEP.115.003808. Circ Arrhythm Electrophysiol. 2016. PMID: 26783234 No abstract available.

4

A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity.

Holmes AP, Yu TY, Tull S, Syeda F, Kuhlmann SM, O'Brien SM, Patel P, Brain KL, Pavlovic D, Brown NA, Fabritz L, Kirchhof P. Holmes AP, et al. PLoS One. 2016 May 5;11(5):e0154077. doi: 10.1371/journal.pone.0154077. eCollection 2016. PLoS One. 2016. PMID: 27149380 Free PMC article.

5

A Simplified, Langendorff-Free Method for Concomitant Isolation of Viable Cardiac Myocytes and Nonmyocytes From the Adult Mouse Heart.

Ackers-Johnson M, Li PY, Holmes AP, O'Brien SM, Pavlovic D, Foo RS. Ackers-Johnson M, et al. Among authors: holmes ap. Circ Res. 2016 Sep 30;119(8):909-20. doi: 10.1161/CIRCRESAHA.116.309202. Epub 2016 Aug 8. Circ Res. 2016. PMID: 27502479 Free PMC article.

6

PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers.

Syeda F, Holmes AP, Yu TY, Tull S, Kuhlmann SM, Pavlovic D, Betney D, Riley G, Kucera JP, Jousset F, de Groot JR, Rohr S, Brown NA, Fabritz L, Kirchhof P. Syeda F, et al. Among authors: holmes ap. J Am Coll Cardiol. 2016 Oct 25;68(17):1881-1894. doi: 10.1016/j.jacc.2016.07.766. J Am Coll Cardiol. 2016. PMID: 27765191 Free PMC article.

7

ElectroMap: High-throughput open-source software for analysis and mapping of cardiac electrophysiology.

O'Shea C, Holmes AP, Yu TY, Winter J, Wells SP, Correia J, Boukens BJ, De Groot JR, Chu GS, Li X, Ng GA, Kirchhof P, Fabritz L, Rajpoot K, Pavlovic D. O'Shea C, et al. Among authors: holmes ap. Sci Rep. 2019 Feb 4;9(1):1389. doi: 10.1038/s41598-018-38263-2. Sci Rep. 2019. PMID: 30718782 Free PMC article.

8

Cardiac Optogenetics and Optical Mapping - Overcoming Spectral Congestion in All-Optical Cardiac Electrophysiology.

O'Shea C, Holmes AP, Winter J, Correia J, Ou X, Dong R, He S, Kirchhof P, Fabritz L, Rajpoot K, Pavlovic D. O'Shea C, et al. Among authors: holmes ap. Front Physiol. 2019 Mar 7;10:182. doi: 10.3389/fphys.2019.00182. eCollection 2019. Front Physiol. 2019. PMID: 30899227 Free PMC article. Review.

9

High-Throughput Analysis of Optical Mapping Data Using ElectroMap.

O'Shea C, Holmes AP, Yu TY, Winter J, Wells SP, Parker BA, Fobian D, Johnson DM, Correia J, Kirchhof P, Fabritz L, Rajpoot K, Pavlovic D. O'Shea C, et al. Among authors: holmes ap. J Vis Exp. 2019 Jun 4;(148). doi: 10.3791/59663. J Vis Exp. 2019. PMID: 31233017

10

Temporal irregularity quantification and mapping of optical action potentials using wave morphology similarity.

O'Shea C, Winter J, Holmes AP, Johnson DM, Correia JN, Kirchhof P, Fabritz L, Rajpoot K, Pavlovic D. O'Shea C, et al. Among authors: holmes ap. Prog Biophys Mol Biol. 2020 Nov;157:84-93. doi: 10.1016/j.pbiomolbio.2019.12.004. Epub 2019 Dec 30. Prog Biophys Mol Biol. 2020. PMID: 31899215 Free PMC article.

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