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FXR mediates ILC-intrinsic responses to intestinal inflammation.
Fu T, Li Y, Oh TG, Cayabyab F, He N, Tang Q, Coulter S, Truitt M, Medina P, He M, Yu RT, Atkins A, Zheng Y, Liddle C, Downes M, Evans RM. Fu T, et al. Among authors: coulter s. Proc Natl Acad Sci U S A. 2022 Dec 20;119(51):e2213041119. doi: 10.1073/pnas.2213041119. Epub 2022 Dec 12. Proc Natl Acad Sci U S A. 2022. PMID: 36508655 Free PMC article.
Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.
Sonoda J, Chong LW, Downes M, Barish GD, Coulter S, Liddle C, Lee CH, Evans RM. Sonoda J, et al. Among authors: coulter s. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2198-203. doi: 10.1073/pnas.0409481102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671183 Free PMC article.
Benefit of farnesoid X receptor inhibition in obstructive cholestasis.
Stedman C, Liddle C, Coulter S, Sonoda J, Alvarez JG, Evans RM, Downes M. Stedman C, et al. Among authors: coulter s. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11323-8. doi: 10.1073/pnas.0604772103. Epub 2006 Jul 14. Proc Natl Acad Sci U S A. 2006. PMID: 16844773 Free PMC article.
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response.
Ding N, Yu RT, Subramaniam N, Sherman MH, Wilson C, Rao R, Leblanc M, Coulter S, He M, Scott C, Lau SL, Atkins AR, Barish GD, Gunton JE, Liddle C, Downes M, Evans RM. Ding N, et al. Among authors: coulter s. Cell. 2013 Apr 25;153(3):601-13. doi: 10.1016/j.cell.2013.03.028. Cell. 2013. PMID: 23622244 Free PMC article.
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance.
Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM. Fang S, et al. Among authors: coulter s. Nat Med. 2015 Feb;21(2):159-65. doi: 10.1038/nm.3760. Epub 2015 Jan 5. Nat Med. 2015. PMID: 25559344 Free PMC article.
204 results