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Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis.
O'Sullivan ED, Mylonas KJ, Bell R, Carvalho C, Baird DP, Cairns C, Gallagher KM, Campbell R, Docherty M, Laird A, Henderson NC, Chandra T, Kirschner K, Conway B, Dihazi GH, Zeisberg M, Hughes J, Denby L, Dihazi H, Ferenbach DA. O'Sullivan ED, et al. Among authors: denby l. JCI Insight. 2022 Nov 22;7(22):e154124. doi: 10.1172/jci.insight.154124. JCI Insight. 2022. PMID: 36509292 Free PMC article.
MicroRNA-214 antagonism protects against renal fibrosis.
Denby L, Ramdas V, Lu R, Conway BR, Grant JS, Dickinson B, Aurora AB, McClure JD, Kipgen D, Delles C, van Rooij E, Baker AH. Denby L, et al. J Am Soc Nephrol. 2014 Jan;25(1):65-80. doi: 10.1681/ASN.2013010072. Epub 2013 Oct 24. J Am Soc Nephrol. 2014. PMID: 24158985 Free PMC article.
Wnt6: another player in the yin and yang of renal Wnt signaling.
Denby L, Conway BR. Denby L, et al. Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F404-5. doi: 10.1152/ajprenal.00296.2016. Epub 2016 Jun 8. Am J Physiol Renal Physiol. 2016. PMID: 27279489 Free article. No abstract available.
Refining the Mouse Subtotal Nephrectomy in Male 129S2/SV Mice for Consistent Modeling of Progressive Kidney Disease With Renal Inflammation and Cardiac Dysfunction.
O'Sullivan J, Finnie SL, Teenan O, Cairns C, Boyd A, Bailey MA, Thomson A, Hughes J, Bénézech C, Conway BR, Denby L. O'Sullivan J, et al. Among authors: denby l. Front Physiol. 2019 Nov 15;10:1365. doi: 10.3389/fphys.2019.01365. eCollection 2019. Front Physiol. 2019. PMID: 31803059 Free PMC article.
Endothelin-1 Mediates the Systemic and Renal Hemodynamic Effects of GPR81 Activation.
Jones NK, Stewart K, Czopek A, Menzies RI, Thomson A, Moran CM, Cairns C, Conway BR, Denby L, Livingstone DEW, Wiseman J, Hadoke PW, Webb DJ, Dhaun N, Dear JW, Mullins JJ, Bailey MA. Jones NK, et al. Among authors: denby l. Hypertension. 2020 May;75(5):1213-1222. doi: 10.1161/HYPERTENSIONAHA.119.14308. Epub 2020 Mar 23. Hypertension. 2020. PMID: 32200679 Free PMC article.
Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants.
Jackson-Jones LH, Smith P, Portman JR, Magalhaes MS, Mylonas KJ, Vermeren MM, Nixon M, Henderson BEP, Dobie R, Vermeren S, Denby L, Henderson NC, Mole DJ, Bénézech C. Jackson-Jones LH, et al. Among authors: denby l. Immunity. 2020 Apr 14;52(4):700-715.e6. doi: 10.1016/j.immuni.2020.03.011. Immunity. 2020. PMID: 32294409 Free PMC article.
Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease.
Conway BR, O'Sullivan ED, Cairns C, O'Sullivan J, Simpson DJ, Salzano A, Connor K, Ding P, Humphries D, Stewart K, Teenan O, Pius R, Henderson NC, Bénézech C, Ramachandran P, Ferenbach D, Hughes J, Chandra T, Denby L. Conway BR, et al. Among authors: denby l. J Am Soc Nephrol. 2020 Dec;31(12):2833-2854. doi: 10.1681/ASN.2020060806. Epub 2020 Sep 25. J Am Soc Nephrol. 2020. PMID: 32978267 Free PMC article.
Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells.
Matthews O, Morrison EE, Tranter JD, Starkey Lewis P, Toor IS, Srivastava A, Sargeant R, Rollison H, Matchett KP, Kendall TJ, Gray GA, Goldring C, Park K, Denby L, Dhaun N, Bailey MA, Henderson NC, Williams D, Dear JW. Matthews O, et al. Among authors: denby l. EBioMedicine. 2020 Dec;62:103092. doi: 10.1016/j.ebiom.2020.103092. Epub 2020 Nov 21. EBioMedicine. 2020. PMID: 33232872 Free PMC article.
57 results