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Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus.
Antiviral Res. 2023 Jan;209:105474. doi: 10.1016/j.antiviral.2022.105474. Epub 2022 Nov 26.
Antiviral Res. 2023.
PMID: 36511318
Free PMC article.
Valspodar limits human cytomegalovirus infection and dissemination.
Parsons AJ, Cohen T, Schwarz TM, Stein KR, Ophir SI, Casado JP, Tortorella D.
Parsons AJ, et al. Among authors: ophir si.
Antiviral Res. 2021 Sep;193:105124. doi: 10.1016/j.antiviral.2021.105124. Epub 2021 Jun 28.
Antiviral Res. 2021.
PMID: 34197862
Free PMC article.
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Development of broadly neutralizing antibodies targeting the cytomegalovirus subdominant antigen gH.
Parsons AJ, Ophir SI, Duty JA, Kraus TA, Stein KR, Moran TM, Tortorella D.
Parsons AJ, et al. Among authors: ophir si.
Commun Biol. 2022 Apr 25;5(1):387. doi: 10.1038/s42003-022-03294-z.
Commun Biol. 2022.
PMID: 35468974
Free PMC article.
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Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants.
Duty JA, Kraus T, Zhou H, Zhang Y, Shaabani N, Yildiz S, Du N, Singh A, Miorin L, Li D, Stegman K, Ophir S, Cao X, Atanasoff K, Lim R, Mena I, Bouvier NM, Kowdle S, Carreño JM, Rivero-Nava L, Raskin A, Moreno E, Johnson S, Rathnasinghe R, Pai CI, Kehrer T, Cabral EP, Jangra S, Healy L, Singh G, Warang P, Simon V, Sordillo EM, van Bakel H, Liu Y, Sun W, Kerwin L, Teijaro J, Schotsaert M, Krammer F, Bresson D, García-Sastre A, Fu Y, Lee B, Powers C, Moran T, Ji H, Tortorella D, Allen R.
Duty JA, et al.
Med. 2022 Oct 14;3(10):705-721.e11. doi: 10.1016/j.medj.2022.08.002. Epub 2022 Aug 8.
Med. 2022.
PMID: 36044897
Free PMC article.
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The CD46 ectodomain participates in human cytomegalovirus infection of epithelial cells.
Parsons AJ, Stein KR, Atanasoff KE, Ophir SI, Casado JP, Tortorella D.
Parsons AJ, et al. Among authors: ophir si.
J Gen Virol. 2023 Sep;104(9):001892. doi: 10.1099/jgv.0.001892.
J Gen Virol. 2023.
PMID: 37668349
Free PMC article.
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A broadly neutralizing human monoclonal antibody generated from transgenic mice immunized with HCMV particles limits virus infection and proliferation.
Atanasoff KE, Parsons AJ, Ophir SI, Lurain N, Kraus T, Moran T, Duty JA, Tortorella D.
Atanasoff KE, et al. Among authors: ophir si.
J Virol. 2024 Jun 4:e0021324. doi: 10.1128/jvi.00213-24. Online ahead of print.
J Virol. 2024.
PMID: 38832789
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