Specks U - Search Results

1

Activation of a Latent Epitope Causing Differential Binding of Antineutrophil Cytoplasmic Antibodies to Proteinase 3.

Casal Moura M, Thompson GE, Nelson DR, Fussner LA, Hummel AM, Jenne DE, Emerling D, Fervenza FC, Kallenberg CGM, Langford CA, McCune WJ, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, Stone JH, Robinson WH, Specks U; WGET and RAVE-ITN Research Groups. Casal Moura M, et al. Among authors: specks u. Arthritis Rheumatol. 2023 May;75(5):748-759. doi: 10.1002/art.42418. Epub 2023 Mar 7. Arthritis Rheumatol. 2023. PMID: 36515151 Free PMC article.

2

Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA.

Specks U, Fass DN, Fautsch MP, Hummel AM, Viss MA. Specks U, et al. FEBS Lett. 1996 Jul 29;390(3):265-70. doi: 10.1016/0014-5793(96)00669-2. FEBS Lett. 1996. PMID: 8706874 Free article.

3

Cloning and functional expression of the murine homologue of proteinase 3: implications for the design of murine models of vasculitis.

Jenne DE, Fröhlich L, Hummel AM, Specks U. Jenne DE, et al. Among authors: specks u. FEBS Lett. 1997 May 19;408(2):187-90. doi: 10.1016/s0014-5793(97)00418-3. FEBS Lett. 1997. PMID: 9187364 Free article.

4

A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide.

Sun J, Fass DN, Viss MA, Hummel AM, Tang H, Homburger HA, Specks U. Sun J, et al. Among authors: specks u. Clin Exp Immunol. 1998 Nov;114(2):320-6. doi: 10.1046/j.1365-2249.1998.00730.x. Clin Exp Immunol. 1998. PMID: 9822293 Free PMC article.

5

Recombinant proteinase 3 produced in different expression systems: recognition by anti-PR3 antibodies.

van der Geld YM, Oost-Kort W, Limburg PC, Specks U, Kallenberg CG. van der Geld YM, et al. Among authors: specks u. J Immunol Methods. 2000 Oct 20;244(1-2):117-31. doi: 10.1016/s0022-1759(00)00261-1. J Immunol Methods. 2000. PMID: 11033024

6

Antineutrophil cytoplasmic antibodies reacting with the pro form of proteinase 3 and disease activity in patients with Wegener's granulomatosis and microscopic polyangiitis.

Russell KA, Fass DN, Specks U. Russell KA, et al. Among authors: specks u. Arthritis Rheum. 2001 Feb;44(2):463-8. doi: 10.1002/1529-0131(200102)44:2<463::AID-ANR65>3.0.CO;2-9. Arthritis Rheum. 2001. PMID: 11229478 Free article.

7

A disease-specific activity index for Wegener's granulomatosis: modification of the Birmingham Vasculitis Activity Score. International Network for the Study of the Systemic Vasculitides (INSSYS).

Stone JH, Hoffman GS, Merkel PA, Min YI, Uhlfelder ML, Hellmann DB, Specks U, Allen NB, Davis JC, Spiera RF, Calabrese LH, Wigley FM, Maiden N, Valente RM, Niles JL, Fye KH, McCune JW, St Clair EW, Luqmani RA; International Network for the Study of the Systemic Vasculitides (INSSYS). Stone JH, et al. Among authors: specks u. Arthritis Rheum. 2001 Apr;44(4):912-20. doi: 10.1002/1529-0131(200104)44:4<912::AID-ANR148>3.0.CO;2-5. Arthritis Rheum. 2001. PMID: 11318006 Free article.

8

Response of Wegener's granulomatosis to anti-CD20 chimeric monoclonal antibody therapy.

Specks U, Fervenza FC, McDonald TJ, Hogan MC. Specks U, et al. Arthritis Rheum. 2001 Dec;44(12):2836-40. doi: 10.1002/1529-0131(200112)44:12<2836::aid-art471>3.0.co;2-w. Arthritis Rheum. 2001. PMID: 11762944 Free article.

9

Effects of carboxy-terminal modifications of proteinase 3 (PR3) on the recognition by PR3-ANCA.

Capizzi SA, Viss MA, Hummel AM, Fass DN, Specks U. Capizzi SA, et al. Among authors: specks u. Kidney Int. 2003 Feb;63(2):756-60. doi: 10.1046/j.1523-1755.2003.00765.x. Kidney Int. 2003. PMID: 12631144 Free article.

10

Evaluation of capture ELISA for detection of antineutrophil cytoplasmic antibodies directed against proteinase 3 in Wegener's granulomatosis: first results from a multicentre study.

Csernok E, Holle J, Hellmich B, Willem J, Tervaert C, Kallenberg CG, Limburg PC, Niles J, Pan G, Specks U, Westman K, Wieslander J, De Groot K, Gross WL. Csernok E, et al. Among authors: specks u. Rheumatology (Oxford). 2004 Feb;43(2):174-80. doi: 10.1093/rheumatology/keh028. Epub 2003 Oct 29. Rheumatology (Oxford). 2004. PMID: 14585921

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