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A concept of dual-responsive prodrugs based on oligomerization-controlled reactivity of ester groups: an improvement of cancer cells versus neutrophils selectivity of camptothecin.
Klemt I, Reshetnikov V, Dutta S, Bila G, Bilyy R, Cuartero IC, Hidalgo A, Wünsche A, Böhm M, Wondrak M, Kunz-Schughart LA, Tietze R, Beierlein F, Imhof P, Gensberger-Reigl S, Pischetsrieder M, Körber M, Jost T, Mokhir A. Klemt I, et al. Among authors: wunsche a. RSC Med Chem. 2024 Jan 31;15(4):1189-1197. doi: 10.1039/d3md00609c. eCollection 2024 Apr 24. RSC Med Chem. 2024. PMID: 38665843 Free PMC article.
A temperate rocky super-Earth transiting a nearby cool star.
Dittmann JA, Irwin JM, Charbonneau D, Bonfils X, Astudillo-Defru N, Haywood RD, Berta-Thompson ZK, Newton ER, Rodriguez JE, Winters JG, Tan TG, Almenara JM, Bouchy F, Delfosse X, Forveille T, Lovis C, Murgas F, Pepe F, Santos NC, Udry S, Wünsche A, Esquerdo GA, Latham DW, Dressing CD. Dittmann JA, et al. Among authors: wunsche a. Nature. 2017 Apr 19;544(7650):333-336. doi: 10.1038/nature22055. Nature. 2017. PMID: 28426003 Free article.
Benefit of transferred mutations is better predicted by the fitness of recipients than by their ecological or genetic relatedness.
Wang Y, Diaz Arenas C, Stoebel DM, Flynn K, Knapp E, Dillon MM, Wünsche A, Hatcher PJ, Moore FB, Cooper VS, Cooper TF. Wang Y, et al. Among authors: wunsche a. Proc Natl Acad Sci U S A. 2016 May 3;113(18):5047-52. doi: 10.1073/pnas.1524988113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27091964 Free PMC article.
37 results