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Microglia regulate central nervous system myelin growth and integrity.
McNamara NB, Munro DAD, Bestard-Cuche N, Uyeda A, Bogie JFJ, Hoffmann A, Holloway RK, Molina-Gonzalez I, Askew KE, Mitchell S, Mungall W, Dodds M, Dittmayer C, Moss J, Rose J, Szymkowiak S, Amann L, McColl BW, Prinz M, Spires-Jones TL, Stenzel W, Horsburgh K, Hendriks JJA, Pridans C, Muramatsu R, Williams A, Priller J, Miron VE. McNamara NB, et al. Among authors: askew ke. Nature. 2023 Jan;613(7942):120-129. doi: 10.1038/s41586-022-05534-y. Epub 2022 Dec 14. Nature. 2023. PMID: 36517604 Free PMC article.
Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment.
Askew KE, Beverley J, Sigfridsson E, Szymkowiak S, Emelianova K, Dando O, Hardingham GE, Duncombe J, Hennessy E, Koudelka J, Samarasekera N, Salman RA, Smith C, Tavares AAS, Gomez-Nicola D, Kalaria RN, McColl BW, Horsburgh K. Askew KE, et al. Glia. 2024 Feb;72(2):375-395. doi: 10.1002/glia.24481. Epub 2023 Nov 1. Glia. 2024. PMID: 37909242 Free PMC article.
Measuring Microglial Turnover in the Adult Brain.
Gomez-Nicola D, Fryatt GL, Askew KE. Gomez-Nicola D, et al. Among authors: askew ke. Methods Mol Biol. 2019;2034:207-215. doi: 10.1007/978-1-4939-9658-2_15. Methods Mol Biol. 2019. PMID: 31392687