Knowles TPJ - Search Results

1

Biomolecular condensate phase diagrams with a combinatorial microdroplet platform.

Arter WE, Qi R, Erkamp NA, Krainer G, Didi K, Welsh TJ, Acker J, Nixon-Abell J, Qamar S, Guillén-Boixet J, Franzmann TM, Kuster D, Hyman AA, Borodavka A, George-Hyslop PS, Alberti S, Knowles TPJ. Arter WE, et al. Among authors: knowles tpj. Nat Commun. 2022 Dec 21;13(1):7845. doi: 10.1038/s41467-022-35265-7. Nat Commun. 2022. PMID: 36543777 Free PMC article.

2

Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers.

Levin A, Mason TO, Adler-Abramovich L, Buell AK, Meisl G, Galvagnion C, Bram Y, Stratford SA, Dobson CM, Knowles TP, Gazit E. Levin A, et al. Nat Commun. 2014 Nov 13;5:5219. doi: 10.1038/ncomms6219. Nat Commun. 2014. PMID: 25391268 Free article.

3

A mechanistic model of tau amyloid aggregation based on direct observation of oligomers.

Shammas SL, Garcia GA, Kumar S, Kjaergaard M, Horrocks MH, Shivji N, Mandelkow E, Knowles TP, Mandelkow E, Klenerman D. Shammas SL, et al. Nat Commun. 2015 Apr 30;6:7025. doi: 10.1038/ncomms8025. Nat Commun. 2015. PMID: 25926130 Free PMC article.

4

Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity.

Yates EV, Müller T, Rajah L, De Genst EJ, Arosio P, Linse S, Vendruscolo M, Dobson CM, Knowles TP. Yates EV, et al. Nat Chem. 2015 Oct;7(10):802-9. doi: 10.1038/nchem.2344. Epub 2015 Sep 14. Nat Chem. 2015. PMID: 26391079

5

Dynamic microfluidic control of supramolecular peptide self-assembly.

Arnon ZA, Vitalis A, Levin A, Michaels TCT, Caflisch A, Knowles TPJ, Adler-Abramovich L, Gazit E. Arnon ZA, et al. Among authors: knowles tpj. Nat Commun. 2016 Oct 25;7:13190. doi: 10.1038/ncomms13190. Nat Commun. 2016. PMID: 27779182 Free PMC article.

6

Oligomer Diversity during the Aggregation of the Repeat Region of Tau.

Kjaergaard M, Dear AJ, Kundel F, Qamar S, Meisl G, Knowles TPJ, Klenerman D. Kjaergaard M, et al. Among authors: knowles tpj. ACS Chem Neurosci. 2018 Dec 19;9(12):3060-3071. doi: 10.1021/acschemneuro.8b00250. Epub 2018 Jul 17. ACS Chem Neurosci. 2018. PMID: 29953200 Free PMC article.

7

Combining Affinity Selection and Specific Ion Mobility for Microchip Protein Sensing.

Arter WE, Charmet J, Kong J, Saar KL, Herling TW, Müller T, Keyser UF, Knowles TPJ. Arter WE, et al. Among authors: knowles tpj. Anal Chem. 2018 Sep 4;90(17):10302-10310. doi: 10.1021/acs.analchem.8b02051. Epub 2018 Aug 15. Anal Chem. 2018. PMID: 30070105

8

Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity.

Ruggeri FS, Charmet J, Kartanas T, Peter Q, Chia S, Habchi J, Dobson CM, Vendruscolo M, Knowles TPJ. Ruggeri FS, et al. Among authors: knowles tpj. Nat Commun. 2018 Sep 24;9(1):3890. doi: 10.1038/s41467-018-06345-4. Nat Commun. 2018. PMID: 30250131 Free PMC article.

9

Mechanobiology of Protein Droplets: Force Arises from Disorder.

Welsh TJ, Shen Y, Levin A, Knowles TPJ. Welsh TJ, et al. Among authors: knowles tpj. Cell. 2018 Nov 29;175(6):1457-1459. doi: 10.1016/j.cell.2018.11.020. Cell. 2018. PMID: 30500530 Free article.

10

Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms.

De S, Wirthensohn DC, Flagmeier P, Hughes C, Aprile FA, Ruggeri FS, Whiten DR, Emin D, Xia Z, Varela JA, Sormanni P, Kundel F, Knowles TPJ, Dobson CM, Bryant C, Vendruscolo M, Klenerman D. De S, et al. Among authors: knowles tpj. Nat Commun. 2019 Apr 4;10(1):1541. doi: 10.1038/s41467-019-09477-3. Nat Commun. 2019. PMID: 30948723 Free PMC article.

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