Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

669 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk.
Rottner AK, Ye Y, Navarro-Guerrero E, Rajesh V, Pollner A, Bevacqua RJ, Yang J, Spigelman AF, Baronio R, Bautista A, Thomsen SK, Lyon J, Nawaz S, Smith N, Wesolowska-Andersen A, Fox JEM, Sun H, Kim SK, Ebner D, MacDonald PE, Gloyn AL. Rottner AK, et al. Among authors: lyon j. Nat Genet. 2023 Jan;55(1):54-65. doi: 10.1038/s41588-022-01261-2. Epub 2022 Dec 21. Nat Genet. 2023. PMID: 36543916 Free PMC article.
Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state.
Dai XQ, Camunas-Soler J, Briant LJB, Dos Santos T, Spigelman AF, Walker EM, Arrojo E Drigo R, Bautista A, Jones RC, Avrahami D, Lyon J, Nie A, Smith N, Zhang Y, Johnson J, Manning Fox JE, Michelakis ED, Light PE, Kaestner KH, Kim SK, Rorsman P, Stein RW, Quake SR, MacDonald PE. Dai XQ, et al. Among authors: lyon j. Cell Metab. 2022 Feb 1;34(2):256-268.e5. doi: 10.1016/j.cmet.2021.12.021. Cell Metab. 2022. PMID: 35108513 Free PMC article.
Functional plasticity of the human infant β-cell exocytotic phenotype.
Fox JE, Seeberger K, Dai XQ, Lyon J, Spigelman AF, Kolic J, Hajmrle C, Joseph JW, Kin T, Shapiro AM, Korbutt G, MacDonald PE. Fox JE, et al. Among authors: lyon j. Endocrinology. 2013 Apr;154(4):1392-9. doi: 10.1210/en.2012-1934. Epub 2013 Feb 28. Endocrinology. 2013. PMID: 23449893
Impacts of the COVID-19 pandemic on a human research islet program.
Dafoe TJ, Dos Santos T, Spigelman AF, Lyon J, Smith N, Bautista A, MacDonald PE, Manning Fox JE. Dafoe TJ, et al. Among authors: lyon j. Islets. 2022 Dec 31;14(1):101-113. doi: 10.1080/19382014.2022.2047571. Islets. 2022. PMID: 35285768 Free PMC article.
Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress.
Shrestha S, Erikson G, Lyon J, Spigelman AF, Bautista A, Manning Fox JE, Dos Santos C, Shokhirev M, Cartailler JP, Hetzer MW, MacDonald PE, Arrojo E Drigo R. Shrestha S, et al. Among authors: lyon j. Sci Adv. 2022 Oct 7;8(40):eabo3932. doi: 10.1126/sciadv.abo3932. Epub 2022 Oct 5. Sci Adv. 2022. PMID: 36197983 Free PMC article.
Cryopreservation and post-thaw characterization of dissociated human islet cells.
Marquez-Curtis LA, Dai XQ, Hang Y, Lam JY, Lyon J, Manning Fox JE, McGann LE, MacDonald PE, Kim SK, Elliott JAW. Marquez-Curtis LA, et al. Among authors: lyon j. PLoS One. 2022 Jan 26;17(1):e0263005. doi: 10.1371/journal.pone.0263005. eCollection 2022. PLoS One. 2022. PMID: 35081145 Free PMC article.
669 results