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SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression.
Cioetto-Mazzabò L, Boldrin F, Beauvineau C, Speth M, Marina A, Namouchi A, Segafreddo G, Cimino M, Favre-Rochex S, Balasingham S, Trastoy B, Munier-Lehmann H, Griffiths G, Gicquel B, Guerin ME, Manganelli R, Alonso-Rodríguez N. Cioetto-Mazzabò L, et al. Among authors: griffiths g. Nucleic Acids Res. 2023 Jan 11;51(1):144-165. doi: 10.1093/nar/gkac1173. Nucleic Acids Res. 2023. PMID: 36546765 Free PMC article.
Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models.
Dal NK, Schäfer G, Thompson AM, Schmitt S, Redinger N, Alonso-Rodriguez N, Johann K, Ojong J, Wohlmann J, Best A, Koynov K, Zentel R, Schaible UE, Griffiths G, Barz M, Fenaroli F. Dal NK, et al. Among authors: griffiths g. J Control Release. 2023 Feb;354:851-868. doi: 10.1016/j.jconrel.2023.01.037. Epub 2023 Feb 1. J Control Release. 2023. PMID: 36681282 Free article.
Supporting self-management of low back pain with an internet intervention with and without telephone support in primary care (SupportBack 2): a randomised controlled trial of clinical and cost-effectiveness.
Geraghty AWA, Becque T, Roberts LC, Hill JC, Foster NE, Yardley L, Stuart B, Turner DA, Hay E, Griffiths G, Webley F, Durcan L, Morgan A, Hughes S, Bathers S, Butler-Walley S, Wathall S, Mansell G, White M, Davies F, Little P. Geraghty AWA, et al. Among authors: griffiths g. Lancet Rheumatol. 2024 May 30:S2665-9913(24)00086-9. doi: 10.1016/S2665-9913(24)00086-9. Online ahead of print. Lancet Rheumatol. 2024. PMID: 38824934 Free article.
Lipid switches in the immunological synapse.
Griffiths G, Brügger B, Freund C. Griffiths G, et al. J Biol Chem. 2024 May 30:107428. doi: 10.1016/j.jbc.2024.107428. Online ahead of print. J Biol Chem. 2024. PMID: 38823638 Free article. Review.
Favorable Antiviral Effect of Metformin on Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of Coronavirus Disease 2019.
Bramante CT, Beckman KB, Mehta T, Karger AB, Odde DJ, Tignanelli CJ, Buse JB, Johnson DM, Watson RHB, Daniel JJ, Liebovitz DM, Nicklas JM, Cohen K, Puskarich MA, Belani HK, Siegel LK, Klatt NR, Anderson B, Hartman KM, Rao V, Hagen AA, Patel B, Fenno SL, Avula N, Reddy NV, Erickson SM, Fricton RD, Lee S, Griffiths G, Pullen MF, Thompson JL, Sherwood NE, Murray TA, Rose MR, Boulware DR, Huling JD; COVID-OUT Study Team. Bramante CT, et al. Among authors: griffiths g. Clin Infect Dis. 2024 May 1:ciae159. doi: 10.1093/cid/ciae159. Online ahead of print. Clin Infect Dis. 2024. PMID: 38690892
Biomarker Predictors of Clinical Efficacy of the Anti-IgE Biologic, Omalizumab, in Severe Asthma in Adults: Results of the SoMOSA Study.
Djukanović R, Brinkman P, Kolmert J, Gomez C, Schofield J, Brandsma J, Shapanis A, Skipp PJS, Postle A, Wheelock C, Dahlén SE, Sterk PJ, Brown T, Jackson DJ, Mansur A, Pavord I, Patel M, Brightling C, Siddiqui S, Bradding P, Sabroe I, Saralaya D, Chishimba L, Porter J, Robinson D, Fowler SJ, Howarth PH, Little L, Oliver T, Hill K, Stanton L, Allen A, Ellis D, Griffiths G, Harrison T, Akenroye A, Lasky-Su J, Heaney L, Chaudhuri R, Kurukulaaratchy R. Djukanović R, et al. Among authors: griffiths g. Am J Respir Crit Care Med. 2024 Apr 18. doi: 10.1164/rccm.202310-1730OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38635834
1,074 results