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SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression.
Cioetto-Mazzabò L, Boldrin F, Beauvineau C, Speth M, Marina A, Namouchi A, Segafreddo G, Cimino M, Favre-Rochex S, Balasingham S, Trastoy B, Munier-Lehmann H, Griffiths G, Gicquel B, Guerin ME, Manganelli R, Alonso-Rodríguez N. Cioetto-Mazzabò L, et al. Among authors: segafreddo g. Nucleic Acids Res. 2023 Jan 11;51(1):144-165. doi: 10.1093/nar/gkac1173. Nucleic Acids Res. 2023. PMID: 36546765 Free PMC article.
The Phosphatidyl-myo-Inositol Dimannoside Acyltransferase PatA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo.
Boldrin F, Anso I, Alebouyeh S, Sevilla IA, Geijo M, Garrido JM, Marina A, Cioetto Mazzabò L, Segafreddo G, Guerin ME, Manganelli R, Prados-Rosales R. Boldrin F, et al. Among authors: segafreddo g. J Bacteriol. 2021 Mar 8;203(7):e00439-20. doi: 10.1128/JB.00439-20. Print 2021 Mar 8. J Bacteriol. 2021. PMID: 33468587 Free PMC article.
SigE: A master regulator of Mycobacterium tuberculosis.
Manganelli R, Cioetto-Mazzabò L, Segafreddo G, Boldrin F, Sorze D, Conflitti M, Serafini A, Provvedi R. Manganelli R, et al. Among authors: segafreddo g. Front Microbiol. 2023 Mar 7;14:1075143. doi: 10.3389/fmicb.2023.1075143. eCollection 2023. Front Microbiol. 2023. PMID: 36960291 Free PMC article. Review.
Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium.
van Wijk RC, Lucía A, Sudhakar PK, Sonnenkalb L, Gaudin C, Hoffmann E, Dremierre B, Aguilar-Ayala DA, Molin MD, Rybniker J, de Giorgi S, Cioetto-Mazzabò L, Segafreddo G, Manganelli R, Degiacomi G, Recchia D, Pasca MR, Simonsson USH, Ramón-García S; ERA4TB consortium. van Wijk RC, et al. Among authors: segafreddo g. iScience. 2023 Mar 15;26(4):106411. doi: 10.1016/j.isci.2023.106411. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091238 Free PMC article.