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Elucidating the Protonation State of the γ-Secretase Catalytic Dyad.
ACS Chem Neurosci. 2023 Jan 18;14(2):261-269. doi: 10.1021/acschemneuro.2c00563. Epub 2022 Dec 23.
ACS Chem Neurosci. 2023.
PMID: 36562727
Effects of the Protonation State of Titratable Residues and the Presence of Water Molecules on Nocodazole Binding to β-Tubulin.
Guzmán-Ocampo DC, Aguayo-Ortiz R, Cano-González L, Castillo R, Hernández-Campos A, Dominguez L.
Guzmán-Ocampo DC, et al.
ChemMedChem. 2018 Jan 8;13(1):20-24. doi: 10.1002/cmdc.201700530. Epub 2017 Nov 23.
ChemMedChem. 2018.
PMID: 29059502
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Toward the Characterization of DAPT Interactions with γ-Secretase.
Aguayo-Ortiz R, Guzmán-Ocampo DC, Dominguez L.
Aguayo-Ortiz R, et al. Among authors: guzman ocampo dc.
ChemMedChem. 2019 May 17;14(10):1005-1010. doi: 10.1002/cmdc.201900106. Epub 2019 Apr 12.
ChemMedChem. 2019.
PMID: 30925201
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Characterizing the Chemical Space of γ-Secretase Inhibitors and Modulators.
Santiago Á, Guzmán-Ocampo DC, Aguayo-Ortiz R, Dominguez L.
Santiago Á, et al. Among authors: guzman ocampo dc.
ACS Chem Neurosci. 2021 Aug 4;12(15):2765-2775. doi: 10.1021/acschemneuro.1c00313. Epub 2021 Jul 22.
ACS Chem Neurosci. 2021.
PMID: 34291906
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Insights into the binding of morin to human γD-crystallin.
Aguayo-Ortiz R, Guzmán-Ocampo DC, Dominguez L.
Aguayo-Ortiz R, et al. Among authors: guzman ocampo dc.
Biophys Chem. 2022 Mar;282:106750. doi: 10.1016/j.bpc.2021.106750. Epub 2021 Dec 29.
Biophys Chem. 2022.
PMID: 34999344
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Filamentous actin destabilization by H2O2 favors DnmA aggregation, with crucial roles of cysteines 450 and 776 in mitochondrial and peroxisomal division in Aspergillus nidulans.
Garrido-Bazán V, Guzmán-Ocampo DC, Domínguez L, Aguirre J.
Garrido-Bazán V, et al. Among authors: guzman ocampo dc.
mBio. 2023 Nov 28;14(6):e0282223. doi: 10.1128/mbio.02822-23. Online ahead of print.
mBio. 2023.
PMID: 38014993
Free PMC article.
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Understanding the Modulatory Role of E2012 on the γ-Secretase-Substrate Interaction.
Guzmán-Ocampo DC, Aguayo-Ortiz R, Dominguez L.
Guzmán-Ocampo DC, et al.
J Chem Inf Model. 2024 May 13;64(9):3855-3864. doi: 10.1021/acs.jcim.3c01993. Epub 2024 Apr 16.
J Chem Inf Model. 2024.
PMID: 38623052
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