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Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits.
Chun S, Akle S, Teodosiadis A, Cade BE, Wang H, Sofer T, Evans DS, Stone KL, Gharib SA, Mukherjee S, Palmer LJ, Hillman D, Rotter JI, Hanis CL, Stamatoyannopoulos JA, Redline S, Cotsapas C, Sunyaev SR. Chun S, et al. Among authors: akle s. PLoS Genet. 2022 Dec 27;18(12):e1010557. doi: 10.1371/journal.pgen.1010557. eCollection 2022 Dec. PLoS Genet. 2022. PMID: 36574455 Free PMC article.
Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy.
Kousi M, Söylemez O, Ozanturk A, Mourtzi N, Akle S, Jungreis I, Muller J, Cassa CA, Brand H, Mokry JA, Wolf MY, Sadeghpour A, McFadden K, Lewis RA, Talkowski ME, Dollfus H, Kellis M, Davis EE, Sunyaev SR, Katsanis N. Kousi M, et al. Among authors: akle s. Nat Genet. 2020 Nov;52(11):1145-1150. doi: 10.1038/s41588-020-0707-1. Epub 2020 Oct 12. Nat Genet. 2020. PMID: 33046855 Free PMC article.
Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood.
Weeks O, Bossé GD, Oderberg IM, Akle S, Houvras Y, Wrighton PJ, LaBella K, Iversen I, Tavakoli S, Adatto I, Schwartz A, Kloosterman D, Tsomides A, Charness ME, Peterson RT, Steinhauser ML, Fazeli PK, Goessling W. Weeks O, et al. Among authors: akle s. J Clin Invest. 2020 May 1;130(5):2252-2269. doi: 10.1172/JCI132139. J Clin Invest. 2020. PMID: 32202514 Free PMC article.
Reconstruction of chemical molecules from images.
Algorri ME, Zimmermann M, Friedrich CM, Akle S, Hofmann-Apitius M. Algorri ME, et al. Among authors: akle s. Annu Int Conf IEEE Eng Med Biol Soc. 2007;2007:4609-12. doi: 10.1109/IEMBS.2007.4353366. Annu Int Conf IEEE Eng Med Biol Soc. 2007. PMID: 18003032