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Excess of heme induces tissue factor-dependent activation of coagulation in mice.
Sparkenbaugh EM, Chantrathammachart P, Wang S, Jonas W, Kirchhofer D, Gailani D, Gruber A, Kasthuri R, Key NS, Mackman N, Pawlinski R. Sparkenbaugh EM, et al. Among authors: gruber a. Haematologica. 2015 Mar;100(3):308-14. doi: 10.3324/haematol.2014.114728. Epub 2015 Jan 16. Haematologica. 2015. PMID: 25596265 Free PMC article.
Factor XI contributes to myocardial ischemia-reperfusion injury in mice.
Lorentz CU, Verbout NG, Cao Z, Liu L, Hinds MT, McCarty OJT, Ivanov I, Tucker EI, Gailani D, Gruber A. Lorentz CU, et al. Among authors: gruber a. Blood Adv. 2018 Jan 23;2(2):85-88. doi: 10.1182/bloodadvances.2017004879. Blood Adv. 2018. PMID: 29365314 Free PMC article.
The protein C activator AB002 rapidly interrupts thrombus development in baboons.
Tucker EI, Verbout NG, Markway BD, Wallisch M, Lorentz CU, Hinds MT, Shatzel JJ, Pelc LA, Wood DC, McCarty OJT, Di Cera E, Gruber A. Tucker EI, et al. Among authors: gruber a. Blood. 2020 Feb 27;135(9):689-699. doi: 10.1182/blood.2019002771. Blood. 2020. PMID: 31977000 Free PMC article. Clinical Trial.
The evolution of factor XI and the kallikrein-kinin system.
Ponczek MB, Shamanaev A, LaPlace A, Dickeson SK, Srivastava P, Sun MF, Gruber A, Kastrup C, Emsley J, Gailani D. Ponczek MB, et al. Among authors: gruber a. Blood Adv. 2020 Dec 22;4(24):6135-6147. doi: 10.1182/bloodadvances.2020002456. Blood Adv. 2020. PMID: 33351111 Free PMC article.
1,242 results