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The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53.
Blood. 2023 May 4;141(18):2245-2260. doi: 10.1182/blood.2022017273.
Blood. 2023.
PMID: 36735909
Free PMC article.
High caspase 3 and vulnerability to dual BCL2 family inhibition define ETO2::GLIS2 pediatric leukemia.
Aid Z, Robert E, Lopez CK, Bourgoin M, Boudia F, Le Mene M, Riviere J, Baille M, Benbarche S, Renou L, Fagnan A, Thirant C, Federici L, Touchard L, Lecluse Y, Jetten A, Geoerger B, Lapillonne H, Solary E, Gaudry M, Meshinchi S, Pflumio F, Auberger P, Lobry C, Petit A, Jacquel A, Mercher T.
Aid Z, et al. Among authors: fagnan a.
Leukemia. 2023 Mar;37(3):571-579. doi: 10.1038/s41375-022-01800-0. Epub 2022 Dec 30.
Leukemia. 2023.
PMID: 36585521
Free PMC article.
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Molecular Landscapes and Models of Acute Erythroleukemia.
Fagnan A, Piqué-Borràs MR, Tauchmann S, Mercher T, Schwaller J.
Fagnan A, et al.
Hemasphere. 2021 Apr 21;5(5):e558. doi: 10.1097/HS9.0000000000000558. eCollection 2021 May.
Hemasphere. 2021.
PMID: 33898929
Free PMC article.
Review.
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NUP98 and KMT2A: usually the bride rather than the bridesmaid.
Fagnan A, Mercher T.
Fagnan A, et al.
Haematologica. 2020 Jul;105(7):1757-1760. doi: 10.3324/haematol.2020.253476.
Haematologica. 2020.
PMID: 32611575
Free PMC article.
No abstract available.
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Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers.
Fagnan A, Bagger FO, Piqué-Borràs MR, Ignacimouttou C, Caulier A, Lopez CK, Robert E, Uzan B, Gelsi-Boyer V, Aid Z, Thirant C, Moll U, Tauchmann S, Kurtovic-Kozaric A, Maciejewski J, Dierks C, Spinelli O, Salmoiraghi S, Pabst T, Shimoda K, Deleuze V, Lapillonne H, Sweeney C, De Mas V, Leite B, Kadri Z, Malinge S, de Botton S, Micol JB, Kile B, Carmichael CL, Iacobucci I, Mullighan CG, Carroll M, Valent P, Bernard OA, Delabesse E, Vyas P, Birnbaum D, Anguita E, Garçon L, Soler E, Schwaller J, Mercher T.
Fagnan A, et al.
Blood. 2020 Aug 6;136(6):698-714. doi: 10.1182/blood.2019003062.
Blood. 2020.
PMID: 32350520
Free PMC article.
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Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia.
Lopez CK, Noguera E, Stavropoulou V, Robert E, Aid Z, Ballerini P, Bilhou-Nabera C, Lapillonne H, Boudia F, Thirant C, Fagnan A, Arcangeli ML, Kinston SJ, Diop M, Job B, Lecluse Y, Brunet E, Babin L, Villeval JL, Delabesse E, Peters AHFM, Vainchenker W, Gaudry M, Masetti R, Locatelli F, Malinge S, Nerlov C, Droin N, Lobry C, Godin I, Bernard OA, Göttgens B, Petit A, Pflumio F, Schwaller J, Mercher T.
Lopez CK, et al. Among authors: fagnan a.
Cancer Discov. 2019 Dec;9(12):1736-1753. doi: 10.1158/2159-8290.CD-18-1463. Epub 2019 Oct 29.
Cancer Discov. 2019.
PMID: 31662298
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PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma.
Hanna JA, Garcia MR, Lardennois A, Leavey PJ, Maglic D, Fagnan A, Go JC, Roach J, Wang YD, Finkelstein D, Hatley ME.
Hanna JA, et al. Among authors: fagnan a.
Oncogene. 2018 Apr;37(15):1991-2007. doi: 10.1038/s41388-017-0081-3. Epub 2018 Jan 25.
Oncogene. 2018.
PMID: 29367756
Free PMC article.
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