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The thromboxane receptor antagonist NTP42 promotes beneficial adaptation and preserves cardiac function in experimental models of right heart overload.
Mulvaney EP, Renzo F, Adão R, Dupre E, Bialesova L, Salvatore V, Reid HM, Conceição G, Grynblat J, Llucià-Valldeperas A, Michel JB, Brás-Silva C, Laurent CE, Howard LS, Montani D, Humbert M, Vonk Noordegraaf A, Perros F, Mendes-Ferreira P, Kinsella BT. Mulvaney EP, et al. Among authors: vonk noordegraaf a. Front Cardiovasc Med. 2022 Dec 14;9:1063967. doi: 10.3389/fcvm.2022.1063967. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36588576 Free PMC article.
Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.
de Man FS, Tu L, Handoko ML, Rain S, Ruiter G, François C, Schalij I, Dorfmüller P, Simonneau G, Fadel E, Perros F, Boonstra A, Postmus PE, van der Velden J, Vonk-Noordegraaf A, Humbert M, Eddahibi S, Guignabert C. de Man FS, et al. Among authors: vonk noordegraaf a. Am J Respir Crit Care Med. 2012 Oct 15;186(8):780-9. doi: 10.1164/rccm.201203-0411OC. Epub 2012 Aug 2. Am J Respir Crit Care Med. 2012. PMID: 22859525 Free PMC article.
Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension.
Germain M, Eyries M, Montani D, Poirier O, Girerd B, Dorfmüller P, Coulet F, Nadaud S, Maugenre S, Guignabert C, Carpentier W, Vonk-Noordegraaf A, Lévy M, Chaouat A, Lambert JC, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Amouyel P, de Ravel TJ, Delcroix M, Austin ED, Robbins IM, Hemnes AR, Loyd JE, Berman-Rosenzweig E, Barst RJ, Chung WK, Simonneau G, Trégouët DA, Humbert M, Soubrier F. Germain M, et al. Among authors: vonk noordegraaf a. Nat Genet. 2013 May;45(5):518-21. doi: 10.1038/ng.2581. Epub 2013 Mar 17. Nat Genet. 2013. PMID: 23502781 Free PMC article.
Diffusion capacity and BMPR2 mutations in pulmonary arterial hypertension.
Trip P, Girerd B, Bogaard HJ, de Man FS, Boonstra A, Garcia G, Humbert M, Montani D, Vonk-Noordegraaf A. Trip P, et al. Among authors: vonk noordegraaf a. Eur Respir J. 2014 Apr;43(4):1195-8. doi: 10.1183/09031936.00136413. Epub 2013 Sep 13. Eur Respir J. 2014. PMID: 24036241 Free article. No abstract available.
Right ventricular diastolic impairment in patients with pulmonary arterial hypertension.
Rain S, Handoko ML, Trip P, Gan CT, Westerhof N, Stienen GJ, Paulus WJ, Ottenheijm CA, Marcus JT, Dorfmüller P, Guignabert C, Humbert M, Macdonald P, Dos Remedios C, Postmus PE, Saripalli C, Hidalgo CG, Granzier HL, Vonk-Noordegraaf A, van der Velden J, de Man FS. Rain S, et al. Among authors: vonk noordegraaf a. Circulation. 2013 Oct 29;128(18):2016-25, 1-10. doi: 10.1161/CIRCULATIONAHA.113.001873. Epub 2013 Sep 20. Circulation. 2013. PMID: 24056688
Protein changes contributing to right ventricular cardiomyocyte diastolic dysfunction in pulmonary arterial hypertension.
Rain S, Bos Dda S, Handoko ML, Westerhof N, Stienen G, Ottenheijm C, Goebel M, Dorfmüller P, Guignabert C, Humbert M, Bogaard HJ, Remedios CD, Saripalli C, Hidalgo CG, Granzier HL, Vonk-Noordegraaf A, van der Velden J, de Man FS. Rain S, et al. Among authors: vonk noordegraaf a. J Am Heart Assoc. 2014 Jun 3;3(3):e000716. doi: 10.1161/JAHA.113.000716. J Am Heart Assoc. 2014. PMID: 24895160 Free PMC article.
Contractile dysfunction of left ventricular cardiomyocytes in patients with pulmonary arterial hypertension.
Manders E, Bogaard HJ, Handoko ML, van de Veerdonk MC, Keogh A, Westerhof N, Stienen GJ, Dos Remedios CG, Humbert M, Dorfmüller P, Fadel E, Guignabert C, van der Velden J, Vonk-Noordegraaf A, de Man FS, Ottenheijm CA. Manders E, et al. Among authors: vonk noordegraaf a. J Am Coll Cardiol. 2014 Jul 8;64(1):28-37. doi: 10.1016/j.jacc.2014.04.031. J Am Coll Cardiol. 2014. PMID: 24998125 Free article.
Characteristics of pulmonary arterial hypertension in affected carriers of a mutation located in the cytoplasmic tail of bone morphogenetic protein receptor type 2.
Girerd B, Coulet F, Jaïs X, Eyries M, Van Der Bruggen C, De Man F, Houweling A, Dorfmüller P, Savale L, Sitbon O, Vonk-Noordegraaf A, Soubrier F, Simonneau G, Humbert M, Montani D. Girerd B, et al. Among authors: vonk noordegraaf a. Chest. 2015 May;147(5):1385-1394. doi: 10.1378/chest.14-0880. Chest. 2015. PMID: 25429696
471 results