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The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus.
Voss LF, Howarth AJ, Wittenborn TR, Hummelgaard S, Juul-Madsen K, Kastberg KS, Pedersen MK, Jensen L, Papanastasiou AD, Vorup-Jensen T, Weyer K, Degn SE. Voss LF, et al. Among authors: juul madsen k. Front Immunol. 2022 Dec 14;13:1021370. doi: 10.3389/fimmu.2022.1021370. eCollection 2022. Front Immunol. 2022. PMID: 36591222 Free PMC article.
The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage.
Christiansen SH, Zhang X, Juul-Madsen K, Hvam ML, Vad BS, Behrens MA, Thygesen IL, Jalilian B, Pedersen JS, Howard KA, Otzen DE, Vorup-Jensen T. Christiansen SH, et al. Biochim Biophys Acta Biomembr. 2017 Mar;1859(3):425-437. doi: 10.1016/j.bbamem.2017.01.001. Epub 2017 Jan 5. Biochim Biophys Acta Biomembr. 2017. PMID: 28064019 Free article.
The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria.
Christiansen SH, Murphy RA, Juul-Madsen K, Fredborg M, Hvam ML, Axelgaard E, Skovdal SM, Meyer RL, Sørensen UBS, Möller A, Nyengaard JR, Nørskov-Lauritsen N, Wang M, Gadjeva M, Howard KA, Davies JC, Petersen E, Vorup-Jensen T. Christiansen SH, et al. Sci Rep. 2017 Nov 15;7(1):15653. doi: 10.1038/s41598-017-15969-3. Sci Rep. 2017. PMID: 29142299 Free PMC article.
Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus.
Juul-Madsen K, Troldborg A, Wittenborn TR, Axelsen MG, Zhao H, Klausen LH, Luecke S, Paludan SR, Stengaard-Pedersen K, Dong M, Møller HJ, Thiel S, Jensen H, Schuck P, Sutherland DS, Degn SE, Vorup-Jensen T. Juul-Madsen K, et al. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2106647118. doi: 10.1073/pnas.2106647118. Proc Natl Acad Sci U S A. 2021. PMID: 34301873 Free PMC article.
18 results