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Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors.
Chan K, Farias AG, Lee H, Guvenc F, Mero P, Brown KR, Ward H, Billmann M, Aulakh K, Astori A, Haider S, Marcon E, Braunschweig U, Pu S, Habsid A, Yan Tong AH, Christie-Holmes N, Budylowski P, Ghalami A, Mubareka S, Maguire F, Banerjee A, Mossman KL, Greenblatt J, Gray-Owen SD, Raught B, Blencowe BJ, Taipale M, Myers C, Moffat J. Chan K, et al. Among authors: braunschweig u. Heliyon. 2023 Jan;9(1):e12744. doi: 10.1016/j.heliyon.2022.e12744. Epub 2022 Dec 30. Heliyon. 2023. PMID: 36597481 Free PMC article.
SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.
Nabeel-Shah S, Lee H, Ahmed N, Burke GL, Farhangmehr S, Ashraf K, Pu S, Braunschweig U, Zhong G, Wei H, Tang H, Yang J, Marcon E, Blencowe BJ, Zhang Z, Greenblatt JF. Nabeel-Shah S, et al. Among authors: braunschweig u. iScience. 2022 Jan 21;25(1):103562. doi: 10.1016/j.isci.2021.103562. Epub 2021 Dec 4. iScience. 2022. PMID: 34901782 Free PMC article.
Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1.
Song J, Nabeel-Shah S, Pu S, Lee H, Braunschweig U, Ni Z, Ahmed N, Marcon E, Zhong G, Ray D, Ha KCH, Guo X, Zhang Z, Hughes TR, Blencowe BJ, Greenblatt JF. Song J, et al. Among authors: braunschweig u. Mol Cell. 2022 Sep 1;82(17):3135-3150.e9. doi: 10.1016/j.molcel.2022.06.031. Epub 2022 Jul 31. Mol Cell. 2022. PMID: 35914531 Free article.
Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons.
Gonatopoulos-Pournatzis T, Wu M, Braunschweig U, Roth J, Han H, Best AJ, Raj B, Aregger M, O'Hanlon D, Ellis JD, Calarco JA, Moffat J, Gingras AC, Blencowe BJ. Gonatopoulos-Pournatzis T, et al. Among authors: braunschweig u. Mol Cell. 2018 Nov 1;72(3):510-524.e12. doi: 10.1016/j.molcel.2018.10.008. Mol Cell. 2018. PMID: 30388412 Free article.
Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis.
Han H, Best AJ, Braunschweig U, Mikolajewicz N, Li JD, Roth J, Chowdhury F, Mantica F, Nabeel-Shah S, Parada G, Brown KR, O'Hanlon D, Wei J, Yao Y, Zid AA, Comsa LC, Jen M, Wang J, Datti A, Gonatopoulos-Pournatzis T, Weatheritt RJ, Greenblatt JF, Wrana JL, Irimia M, Gingras AC, Moffat J, Blencowe BJ. Han H, et al. Among authors: braunschweig u. Mol Cell. 2022 Aug 18;82(16):2982-2999.e14. doi: 10.1016/j.molcel.2022.06.036. Epub 2022 Jul 31. Mol Cell. 2022. PMID: 35914530 Free PMC article.
Widespread intron retention in mammals functionally tunes transcriptomes.
Braunschweig U, Barbosa-Morais NL, Pan Q, Nachman EN, Alipanahi B, Gonatopoulos-Pournatzis T, Frey B, Irimia M, Blencowe BJ. Braunschweig U, et al. Genome Res. 2014 Nov;24(11):1774-86. doi: 10.1101/gr.177790.114. Epub 2014 Sep 25. Genome Res. 2014. PMID: 25258385 Free PMC article.
Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors.
Han H, Braunschweig U, Gonatopoulos-Pournatzis T, Weatheritt RJ, Hirsch CL, Ha KCH, Radovani E, Nabeel-Shah S, Sterne-Weiler T, Wang J, O'Hanlon D, Pan Q, Ray D, Zheng H, Vizeacoumar F, Datti A, Magomedova L, Cummins CL, Hughes TR, Greenblatt JF, Wrana JL, Moffat J, Blencowe BJ. Han H, et al. Among authors: braunschweig u. Mol Cell. 2017 Feb 2;65(3):539-553.e7. doi: 10.1016/j.molcel.2017.01.011. Mol Cell. 2017. PMID: 28157508 Free article.
32 results