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The C-Type Lectin Receptor Dectin-2 Is a Receptor for Aspergillus fumigatus Galactomannan.
Reedy JL, Crossen AJ, Negoro PE, Harding HB, Ward RA, Vargas-Blanco DA, Timmer KD, Reardon CM, Basham KJ, Mansour MK, Wüthrich M, Fontaine T, Latgé JP, Vyas JM. Reedy JL, et al. Among authors: crossen aj. mBio. 2023 Feb 28;14(1):e0318422. doi: 10.1128/mbio.03184-22. Epub 2023 Jan 4. mBio. 2023. PMID: 36598192 Free PMC article.
BTK inhibitor-induced defects in human neutrophil effector activity against Aspergillus fumigatus are restored by TNFα.
Vargas-Blanco DA, Hepworth OW, Basham KJ, Simaku P, Crossen AJ, Timmer KD, Hopke A, Brown Harding H, Vandal SR, Jensen KN, Floyd DJ, Reedy JL, Reardon C, Mansour MK, Ward RA, Irimia D, Abramson JS, Vyas JM. Vargas-Blanco DA, et al. Among authors: crossen aj. JCI Insight. 2024 May 7:e176162. doi: 10.1172/jci.insight.176162. Online ahead of print. JCI Insight. 2024. PMID: 38713531 Free article.
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING.
Brown Harding H, Kwaku GN, Reardon CM, Khan NS, Zamith-Miranda D, Zarnowski R, Tam JM, Bohaen CK, Richey L, Mosallanejad K, Crossen AJ, Reedy JL, Ward RA, Vargas-Blanco DA, Basham KJ, Bhattacharyya RP, Nett JE, Mansour MK, van de Veerdonk FL, Kumar V, Kagan JC, Andes DR, Nosanchuk JD, Vyas JM. Brown Harding H, et al. Among authors: crossen aj. Nat Microbiol. 2024 Jan;9(1):95-107. doi: 10.1038/s41564-023-01546-0. Epub 2024 Jan 2. Nat Microbiol. 2024. PMID: 38168615 Free PMC article.
Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing.
Reedy JL, Jensen KN, Crossen AJ, Basham KJ, Ward RA, Reardon CM, Harding HB, Hepworth OW, Simaku P, Kwaku GN, Tone K, Willment JA, Reid DM, Stappers MHT, Brown GD, Rajagopal J, Vyas JM. Reedy JL, et al. Among authors: crossen aj. bioRxiv [Preprint]. 2024 May 6:2023.03.28.534632. doi: 10.1101/2023.03.28.534632. bioRxiv. 2024. PMID: 37034634 Free PMC article. Preprint.