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Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells.
Sellar RS, Sperling AS, Słabicki M, Gasser JA, McConkey ME, Donovan KA, Mageed N, Adams DN, Zou C, Miller PG, Dutta RK, Boettcher S, Lin AE, Sandoval B, Quevedo Barrios VA, Kovalcik V, Koeppel J, Henderson EK, Fink EC, Yang L, Chan A, Pokharel SP, Bergstrom EJ, Burt R, Udeshi ND, Carr SA, Fischer ES, Chen CW, Ebert BL. Sellar RS, et al. J Clin Invest. 2022 Aug 15;132(16):e153514. doi: 10.1172/JCI153514. J Clin Invest. 2022. PMID: 35763353 Free PMC article.
Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput.
Kennedy PH, Alborzian Deh Sheikh A, Balakar M, Jones AC, Olive ME, Hegde M, Matias MI, Pirete N, Burt R, Levy J, Little T, Hogan PG, Liu DR, Doench JG, Newton AC, Gottschalk RA, de Boer CG, Alarcón S, Newby GA, Myers SA. Kennedy PH, et al. Among authors: burt r. Nat Methods. 2024 Apr 29. doi: 10.1038/s41592-024-02256-z. Online ahead of print. Nat Methods. 2024. PMID: 38684783
ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell death.
Ogier JM, Gao Y, Dunne EM, Wilson MA, Ranganathan SC, Tesch GH, Nikolic Paterson DJ, Dabdoub A, Burt RA, Nayagam BA, Lockhart PJ. Ogier JM, et al. Among authors: burt ra. J Mol Med (Berl). 2022 May;100(5):797-813. doi: 10.1007/s00109-022-02188-1. Epub 2022 Apr 26. J Mol Med (Berl). 2022. PMID: 35471608 Free PMC article.
Organotypic Culture of Neonatal Murine Inner Ear Explants.
Ogier JM, Burt RA, Drury HR, Lim R, Nayagam BA. Ogier JM, et al. Among authors: burt ra. Front Cell Neurosci. 2019 May 3;13:170. doi: 10.3389/fncel.2019.00170. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31130846 Free PMC article.
91 results