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Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity.
Shinoda K, Li R, Rezk A, Mexhitaj I, Patterson KR, Kakara M, Zuroff L, Bennett JL, von Büdingen HC, Carruthers R, Edwards KR, Fallis R, Giacomini PS, Greenberg BM, Hafler DA, Ionete C, Kaunzner UW, Lock CB, Longbrake EE, Pardo G, Piehl F, Weber MS, Ziemssen T, Jacobs D, Gelfand JM, Cross AH, Cameron B, Musch B, Winger RC, Jia X, Harp CT, Herman A, Bar-Or A. Shinoda K, et al. Among authors: winger rc. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2207291120. doi: 10.1073/pnas.2207291120. Epub 2023 Jan 12. Proc Natl Acad Sci U S A. 2023. PMID: 36634138 Free PMC article.
Depletion of B lymphocytes from cerebral perivascular spaces by rituximab.
Martin Mdel P, Cravens PD, Winger R, Kieseier BC, Cepok S, Eagar TN, Zamvil SS, Weber MS, Frohman EM, Kleinschmidt-Demasters BK, Montine TJ, Hemmer B, Marra CM, Stüve O. Martin Mdel P, et al. Arch Neurol. 2009 Aug;66(8):1016-20. doi: 10.1001/archneurol.2009.157. Arch Neurol. 2009. PMID: 19667224
Antibodies in multiple sclerosis oligoclonal bands target debris.
Winger RC, Zamvil SS. Winger RC, et al. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7696-8. doi: 10.1073/pnas.1609246113. Epub 2016 Jun 28. Proc Natl Acad Sci U S A. 2016. PMID: 27357674 Free PMC article. No abstract available.
Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4.
Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman AS, Steinman L, Green AJ, Anderson MS, Sobel RA, Zamvil SS. Sagan SA, et al. Among authors: winger rc. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14781-14786. doi: 10.1073/pnas.1617859114. Epub 2016 Dec 8. Proc Natl Acad Sci U S A. 2016. PMID: 27940915 Free PMC article.
The FLUENT study design: investigating immune cell subset and neurofilament changes in patients with relapsing multiple sclerosis treated with fingolimod.
Cohen JA, Bar-Or A, Cree BAC, Mao-Draayer Y, Han MH, Singer B, Jannu A, Kolodny S, Meng X, Winger RC. Cohen JA, et al. Among authors: winger rc. Mult Scler J Exp Transl Clin. 2019 Jan 2;5(1):2055217318819245. doi: 10.1177/2055217318819245. eCollection 2019 Jan-Mar. Mult Scler J Exp Transl Clin. 2019. PMID: 30637116 Free PMC article.
The CELLO trial: Protocol of a planned phase 4 study to assess the efficacy of Ocrelizumab in patients with radiologically isolated syndrome.
Longbrake EE, Hua LH, Mowry EM, Gauthier SA, Alvarez E, Cross AH, Pei J, Priest J, Raposo C, Hafler DA, Winger RC. Longbrake EE, et al. Among authors: winger rc. Mult Scler Relat Disord. 2022 Dec;68:104143. doi: 10.1016/j.msard.2022.104143. Epub 2022 Aug 22. Mult Scler Relat Disord. 2022. PMID: 36031693 Free PMC article.
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