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Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood.
Daskalakis NP, Iatrou A, Chatzinakos C, Jajoo A, Snijders C, Wylie D, DiPietro CP, Tsatsani I, Chen CY, Pernia CD, Soliva-Estruch M, Arasappan D, Bharadwaj RA, Collado-Torres L, Wuchty S, Alvarez VE, Dammer EB, Deep-Soboslay A, Duong DM, Eagles N, Huber BR, Huuki L, Holstein VL, Logue MW, Lugenbühl JF, Maihofer AX, Miller MW, Nievergelt CM, Pertea G, Ross D, Sendi MSE, Sun BB, Tao R, Tooke J, Wolf EJ, Zeier Z; PTSD Working Group of Psychiatric Genomics Consortium**; Berretta S, Champagne FA, Hyde T, Seyfried NT, Shin JH, Weinberger DR, Nemeroff CB, Kleinman JE, Ressler KJ; PTSD Working Group of Psychiatric Genomics Consortium. Daskalakis NP, et al. Among authors: holstein vl. Science. 2024 May 24;384(6698):eadh3707. doi: 10.1126/science.adh3707. Epub 2024 May 24. Science. 2024. PMID: 38781393
Genetic, individual, and familial risk correlates of brain network controllability in major depressive disorder.
Hahn T, Winter NR, Ernsting J, Gruber M, Mauritz MJ, Fisch L, Leenings R, Sarink K, Blanke J, Holstein V, Emden D, Beisemann M, Opel N, Grotegerd D, Meinert S, Heindel W, Witt S, Rietschel M, Nöthen MM, Forstner AJ, Kircher T, Nenadic I, Jansen A, Müller-Myhsok B, Andlauer TFM, Walter M, van den Heuvel MP, Jamalabadi H, Dannlowski U, Repple J. Hahn T, et al. Among authors: holstein v. Mol Psychiatry. 2023 Mar;28(3):1057-1063. doi: 10.1038/s41380-022-01936-6. Epub 2023 Jan 13. Mol Psychiatry. 2023. PMID: 36639510 Free PMC article.
An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling.
Hahn T, Ernsting J, Winter NR, Holstein V, Leenings R, Beisemann M, Fisch L, Sarink K, Emden D, Opel N, Redlich R, Repple J, Grotegerd D, Meinert S, Hirsch JG, Niendorf T, Endemann B, Bamberg F, Kröncke T, Bülow R, Völzke H, von Stackelberg O, Sowade RF, Umutlu L, Schmidt B, Caspers S, Kugel H, Kircher T, Risse B, Gaser C, Cole JH, Dannlowski U, Berger K. Hahn T, et al. Among authors: holstein v. Sci Adv. 2022 Jan 7;8(1):eabg9471. doi: 10.1126/sciadv.abg9471. Epub 2022 Jan 5. Sci Adv. 2022. PMID: 34985964 Free PMC article.
PHOTONAI-A Python API for rapid machine learning model development.
Leenings R, Winter NR, Plagwitz L, Holstein V, Ernsting J, Sarink K, Fisch L, Steenweg J, Kleine-Vennekate L, Gebker J, Emden D, Grotegerd D, Opel N, Risse B, Jiang X, Dannlowski U, Hahn T. Leenings R, et al. Among authors: holstein v. PLoS One. 2021 Jul 21;16(7):e0254062. doi: 10.1371/journal.pone.0254062. eCollection 2021. PLoS One. 2021. PMID: 34288935 Free PMC article.
Association Between Genetic Risk for Type 2 Diabetes and Structural Brain Connectivity in Major Depressive Disorder.
Repple J, König A, de Lange SC, Opel N, Redlich R, Meinert S, Grotegerd D, Mauritz M, Hahn T, Borgers T, Leehr EJ, Winter N, Goltermann J, Enneking V, Fingas SM, Lemke H, Waltemate L, Dohm K, Richter M, Mehler DMA, Holstein V, Gruber M, Nenadic I, Krug A, Brosch K, Schmitt S, Stein F, Meller T, Jansen A, Steinsträter O, Amare AT, Kircher T, Baune BT, van den Heuvel MP, Dannlowski U. Repple J, et al. Among authors: holstein v. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Mar;7(3):333-340. doi: 10.1016/j.bpsc.2021.02.010. Epub 2021 Mar 5. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022. PMID: 33684623