Locasale JW - Search Results

1

Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation.

Meyers AK, Wang Z, Han W, Zhao Q, Zabalawi M, Duan L, Liu J, Zhang Q, Manne RK, Lorenzo F, Quinn MA, Song Q, Fan D, Lin HK, Furdui CM, Locasale JW, McCall CE, Zhu X. Meyers AK, et al. Among authors: locasale jw. Cell Rep. 2023 Jan 31;42(1):111941. doi: 10.1016/j.celrep.2022.111941. Epub 2023 Jan 9. Cell Rep. 2023. PMID: 36640341 Free PMC article.

2

ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer.

Park S, Chang CY, Safi R, Liu X, Baldi R, Jasper JS, Anderson GR, Liu T, Rathmell JC, Dewhirst MW, Wood KC, Locasale JW, McDonnell DP. Park S, et al. Among authors: locasale jw. Cell Rep. 2016 Apr 12;15(2):323-35. doi: 10.1016/j.celrep.2016.03.026. Epub 2016 Mar 31. Cell Rep. 2016. PMID: 27050525 Free PMC article.

3

Glucose Metabolism in Cancer: The Saga of Pyruvate Kinase Continues.

Allen AE, Locasale JW. Allen AE, et al. Among authors: locasale jw. Cancer Cell. 2018 Mar 12;33(3):337-339. doi: 10.1016/j.ccell.2018.02.008. Cancer Cell. 2018. PMID: 29533776 Free PMC article.

4

Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism.

Gao X, Lee K, Reid MA, Sanderson SM, Qiu C, Li S, Liu J, Locasale JW. Gao X, et al. Among authors: locasale jw. Cell Rep. 2018 Mar 27;22(13):3507-3520. doi: 10.1016/j.celrep.2018.03.017. Cell Rep. 2018. PMID: 29590619 Free PMC article.

5

Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals.

Liu X, Cooper DE, Cluntun AA, Warmoes MO, Zhao S, Reid MA, Liu J, Lund PJ, Lopes M, Garcia BA, Wellen KE, Kirsch DG, Locasale JW. Liu X, et al. Among authors: locasale jw. Cell. 2018 Oct 4;175(2):502-513.e13. doi: 10.1016/j.cell.2018.08.040. Epub 2018 Sep 20. Cell. 2018. PMID: 30245009 Free PMC article.

6

Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1.

Freemerman AJ, Zhao L, Pingili AK, Teng B, Cozzo AJ, Fuller AM, Johnson AR, Milner JJ, Lim MF, Galanko JA, Beck MA, Bear JE, Rotty JD, Bezavada L, Smallwood HS, Puchowicz MA, Liu J, Locasale JW, Lee DP, Bennett BJ, Abel ED, Rathmell JC, Makowski L. Freemerman AJ, et al. Among authors: locasale jw. J Immunol. 2019 Feb 15;202(4):1265-1286. doi: 10.4049/jimmunol.1800002. Epub 2019 Jan 18. J Immunol. 2019. PMID: 30659108 Free PMC article.

7

Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer.

Park S, Safi R, Liu X, Baldi R, Liu W, Liu J, Locasale JW, Chang CY, McDonnell DP. Park S, et al. Among authors: locasale jw. Cell Rep. 2019 Jun 18;27(12):3587-3601.e4. doi: 10.1016/j.celrep.2019.05.066. Cell Rep. 2019. PMID: 31216477 Free PMC article.

8

Exposure of Pancreatic β-Cells to Excess Glucose Results in Bimodal Activation of mTORC1 and mTOR-Dependent Metabolic Acceleration.

Rumala CZ, Liu J, Locasale JW, Corkey BE, Deeney JT, Rameh LE. Rumala CZ, et al. Among authors: locasale jw. iScience. 2020 Feb 21;23(2):100858. doi: 10.1016/j.isci.2020.100858. Epub 2020 Jan 22. iScience. 2020. PMID: 32058969 Free PMC article.

9

NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism.

Fox DB, Garcia NMG, McKinney BJ, Lupo R, Noteware LC, Newcomb R, Liu J, Locasale JW, Hirschey MD, Alvarez JV. Fox DB, et al. Among authors: locasale jw. Nat Metab. 2020 Apr;2(4):318-334. doi: 10.1038/s42255-020-0191-z. Epub 2020 Apr 20. Nat Metab. 2020. PMID: 32691018 Free PMC article.

10

Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line.

Gu C, Liu J, Liu X, Zhang H, Luo J, Wang H, Locasale JW, Shears SB. Gu C, et al. Among authors: locasale jw. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2020187118. doi: 10.1073/pnas.2020187118. Proc Natl Acad Sci U S A. 2021. PMID: 33649228 Free PMC article.

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