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Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity.
Iqbal F, Schlotter F, Becker-Greene D, Lupieri A, Goettsch C, Hutcheson JD, Rogers MA, Itoh S, Halu A, Lee LH, Blaser MC, Mlynarchik AK, Hagita S, Kuraoka S, Chen HY, Engert JC, Passos LSA, Jha PK, Osborn EA, Jaffer FA, Body SC, Robson SC, Thanassoulis G, Aikawa M, Singh SA, Sonawane AR, Aikawa E. Iqbal F, et al. Among authors: hutcheson jd. Eur Heart J. 2023 Mar 7;44(10):885-898. doi: 10.1093/eurheartj/ehac818. Eur Heart J. 2023. PMID: 36660854 Free PMC article.
Potential drug targets for calcific aortic valve disease.
Hutcheson JD, Aikawa E, Merryman WD. Hutcheson JD, et al. Nat Rev Cardiol. 2014 Apr;11(4):218-31. doi: 10.1038/nrcardio.2014.1. Epub 2014 Jan 21. Nat Rev Cardiol. 2014. PMID: 24445487 Free PMC article. Review.
Valvular interstitial cells suppress calcification of valvular endothelial cells.
Hjortnaes J, Shapero K, Goettsch C, Hutcheson JD, Keegan J, Kluin J, Mayer JE, Bischoff J, Aikawa E. Hjortnaes J, et al. Among authors: hutcheson jd. Atherosclerosis. 2015 Sep;242(1):251-260. doi: 10.1016/j.atherosclerosis.2015.07.008. Epub 2015 Jul 17. Atherosclerosis. 2015. PMID: 26232165 Free PMC article.
73 results