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Page 1
Mammalian life depends on two distinct pathways of DNA damage tolerance.
Buoninfante OA, Pilzecker B, Spanjaard A, de Groot D, Prekovic S, Song JY, Lieftink C, Ayidah M, Pritchard CEJ, Vivié J, Mcgrath KE, Huijbers IJ, Philipsen S, von Lindern M, Zwart W, Beijersbergen RL, Palis J, van den Berk PCM, Jacobs H. Buoninfante OA, et al. Among authors: philipsen s. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2216055120. doi: 10.1073/pnas.2216055120. Epub 2023 Jan 20. Proc Natl Acad Sci U S A. 2023. PMID: 36669105 Free PMC article.
Hemoglobin switching in mice carrying the Klf1Nan variant.
Korporaal A, Gillemans N, Heshusius S, Cantú I, van den Akker E, van Dijk TB, von Lindern M, Philipsen S. Korporaal A, et al. Among authors: philipsen s. Haematologica. 2021 Feb 1;106(2):464-473. doi: 10.3324/haematol.2019.239830. Haematologica. 2021. PMID: 32467144 Free PMC article.
Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity.
Pourfarzad F, von Lindern M, Azarkeivan A, Hou J, Kia SK, Esteghamat F, van Ijcken W, Philipsen S, Najmabadi H, Grosveld F. Pourfarzad F, et al. Among authors: philipsen s. Haematologica. 2013 May;98(5):696-704. doi: 10.3324/haematol.2012.074492. Epub 2012 Oct 25. Haematologica. 2013. PMID: 23100274 Free PMC article.
Dynamic regulation of Gata factor levels is more important than their identity.
Ferreira R, Wai A, Shimizu R, Gillemans N, Rottier R, von Lindern M, Ohneda K, Grosveld F, Yamamoto M, Philipsen S. Ferreira R, et al. Among authors: philipsen s. Blood. 2007 Jun 15;109(12):5481-90. doi: 10.1182/blood-2006-11-060491. Epub 2007 Feb 27. Blood. 2007. PMID: 17327407 Free article.
Fetal globin expression is regulated by Friend of Prmt1.
van Dijk TB, Gillemans N, Pourfarzad F, van Lom K, von Lindern M, Grosveld F, Philipsen S. van Dijk TB, et al. Among authors: philipsen s. Blood. 2010 Nov 18;116(20):4349-52. doi: 10.1182/blood-2010-03-274399. Epub 2010 Aug 5. Blood. 2010. PMID: 20688955 Free PMC article.
The DNA binding factor Hmg20b is a repressor of erythroid differentiation.
Esteghamat F, van Dijk TB, Braun H, Dekker S, van der Linden R, Hou J, Fanis P, Demmers J, van IJcken W, Ozgür Z, Horos R, Pourfarzad F, von Lindern M, Philipsen S. Esteghamat F, et al. Among authors: philipsen s. Haematologica. 2011 Sep;96(9):1252-60. doi: 10.3324/haematol.2011.045211. Epub 2011 May 23. Haematologica. 2011. PMID: 21606163 Free PMC article.
The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation.
Cantú I, van de Werken HJG, Gillemans N, Stadhouders R, Heshusius S, Maas A, Esteghamat F, Ozgur Z, van IJcken WFJ, Grosveld F, von Lindern M, Philipsen S, van Dijk TB. Cantú I, et al. Among authors: philipsen s. PLoS One. 2019 Mar 28;14(3):e0208659. doi: 10.1371/journal.pone.0208659. eCollection 2019. PLoS One. 2019. PMID: 30921348 Free PMC article.
Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice.
Esteghamat F, Gillemans N, Bilic I, van den Akker E, Cantù I, van Gent T, Klingmüller U, van Lom K, von Lindern M, Grosveld F, Bryn van Dijk T, Busslinger M, Philipsen S. Esteghamat F, et al. Among authors: philipsen s. Blood. 2013 Mar 28;121(13):2553-62. doi: 10.1182/blood-2012-06-434530. Epub 2013 Jan 29. Blood. 2013. PMID: 23361909 Free article.
141 results