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Phase Separation in Biology and Disease; Current Perspectives and Open Questions.
Boeynaems S, Chong S, Gsponer J, Holt L, Milovanovic D, Mitrea DM, Mueller-Cajar O, Portz B, Reilly JF, Reinkemeier CD, Sabari BR, Sanulli S, Shorter J, Sontag E, Strader L, Stachowiak J, Weber SC, White M, Zhang H, Zweckstetter M, Elbaum-Garfinkle S, Kriwacki R. Boeynaems S, et al. Among authors: sabari br. J Mol Biol. 2023 Mar 1;435(5):167971. doi: 10.1016/j.jmb.2023.167971. Epub 2023 Jan 21. J Mol Biol. 2023. PMID: 36690068 Free PMC article.
Is transcriptional regulation just going through a phase?
Narlikar GJ, Myong S, Larson D, Maeshima K, Francis N, Rippe K, Sabari B, Strader L, Tjian R. Narlikar GJ, et al. Mol Cell. 2021 Apr 15;81(8):1579-1585. doi: 10.1016/j.molcel.2021.03.046. Mol Cell. 2021. PMID: 33861943 Free article. No abstract available.
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains.
Boija A, Klein IA, Sabari BR, Dall'Agnese A, Coffey EL, Zamudio AV, Li CH, Shrinivas K, Manteiga JC, Hannett NM, Abraham BJ, Afeyan LK, Guo YE, Rimel JK, Fant CB, Schuijers J, Lee TI, Taatjes DJ, Young RA. Boija A, et al. Among authors: sabari br. Cell. 2018 Dec 13;175(7):1842-1855.e16. doi: 10.1016/j.cell.2018.10.042. Epub 2018 Nov 15. Cell. 2018. PMID: 30449618 Free PMC article.
Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes.
Zamudio AV, Dall'Agnese A, Henninger JE, Manteiga JC, Afeyan LK, Hannett NM, Coffey EL, Li CH, Oksuz O, Sabari BR, Boija A, Klein IA, Hawken SW, Spille JH, Decker TM, Cisse II, Abraham BJ, Lee TI, Taatjes DJ, Schuijers J, Young RA. Zamudio AV, et al. Among authors: sabari br. Mol Cell. 2019 Dec 5;76(5):753-766.e6. doi: 10.1016/j.molcel.2019.08.016. Epub 2019 Sep 25. Mol Cell. 2019. PMID: 31563432 Free PMC article.
Coactivator condensation at super-enhancers links phase separation and gene control.
Sabari BR, Dall'Agnese A, Boija A, Klein IA, Coffey EL, Shrinivas K, Abraham BJ, Hannett NM, Zamudio AV, Manteiga JC, Li CH, Guo YE, Day DS, Schuijers J, Vasile E, Malik S, Hnisz D, Lee TI, Cisse II, Roeder RG, Sharp PA, Chakraborty AK, Young RA. Sabari BR, et al. Science. 2018 Jul 27;361(6400):eaar3958. doi: 10.1126/science.aar3958. Epub 2018 Jun 21. Science. 2018. PMID: 29930091 Free PMC article.
Biomolecular Condensates in the Nucleus.
Sabari BR, Dall'Agnese A, Young RA. Sabari BR, et al. Trends Biochem Sci. 2020 Nov;45(11):961-977. doi: 10.1016/j.tibs.2020.06.007. Epub 2020 Jul 17. Trends Biochem Sci. 2020. PMID: 32684431 Free PMC article. Review.
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