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Mitochondrial control of immunity: beyond ATP.
Mehta MM, Weinberg SE, Chandel NS. Mehta MM, et al. Among authors: weinberg se. Nat Rev Immunol. 2017 Oct;17(10):608-620. doi: 10.1038/nri.2017.66. Epub 2017 Jul 3. Nat Rev Immunol. 2017. PMID: 28669986 Review.
Mediator complex subunit 1 architects a tumorigenic Treg cell program independent of inflammation.
Chaudhuri SM, Weinberg SE, Wang D, Yalom LK, Montauti E, Iyer R, Tang AY, Torres Acosta MA, Shen J, Mani NL, Wang S, Liu K, Lu W, Bui TM, Manzanares LD, Dehghani Z, Wai CM, Gao B, Wei J, Yue F, Cui W, Singer BD, Sumagin R, Zhang Y, Fang D. Chaudhuri SM, et al. Among authors: weinberg se. Cell Rep Med. 2024 Mar 19;5(3):101441. doi: 10.1016/j.xcrm.2024.101441. Epub 2024 Feb 29. Cell Rep Med. 2024. PMID: 38428427 Free PMC article.
Single-cell profiling reveals inflammatory polarization of human carotid versus femoral plaque leukocytes.
Slysz J, Sinha A, DeBerge M, Singh S, Avgousti H, Lee I, Glinton K, Nagasaka R, Dalal P, Alexandria S, Wai CM, Tellez R, Vescovo M, Sunderraj A, Wang X, Schipma M, Sisk R, Gulati R, Vallejo J, Saigusa R, Lloyd-Jones DM, Lomasney J, Weinberg S, Ho K, Ley K, Giannarelli C, Thorp EB, Feinstein MJ. Slysz J, et al. JCI Insight. 2023 Sep 8;8(17):e171359. doi: 10.1172/jci.insight.171359. JCI Insight. 2023. PMID: 37471165 Free PMC article.
AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental stress.
Torres Acosta MA, Mambetsariev N, Reyes Flores CP, Helmin KA, Liu Q, Joudi AM, Morales-Nebreda L, Gurkan J, Cheng K, Abdala-Valencia H, Weinberg SE, Singer BD. Torres Acosta MA, et al. Among authors: weinberg se. bioRxiv [Preprint]. 2023 Dec 1:2023.11.29.568904. doi: 10.1101/2023.11.29.568904. bioRxiv. 2023. PMID: 38076988 Free PMC article. Preprint.
Hexokinase 1 cellular localization regulates the metabolic fate of glucose.
De Jesus A, Keyhani-Nejad F, Pusec CM, Goodman L, Geier JA, Stoolman JS, Stanczyk PJ, Nguyen T, Xu K, Suresh KV, Chen Y, Rodriguez AE, Shapiro JS, Chang HC, Chen C, Shah KP, Ben-Sahra I, Layden BT, Chandel NS, Weinberg SE, Ardehali H. De Jesus A, et al. Among authors: weinberg se. Mol Cell. 2022 Apr 7;82(7):1261-1277.e9. doi: 10.1016/j.molcel.2022.02.028. Epub 2022 Mar 18. Mol Cell. 2022. PMID: 35305311 Free PMC article.
Mitochondrial complex III is essential for suppressive function of regulatory T cells.
Weinberg SE, Singer BD, Steinert EM, Martinez CA, Mehta MM, Martínez-Reyes I, Gao P, Helmin KA, Abdala-Valencia H, Sena LA, Schumacker PT, Turka LA, Chandel NS. Weinberg SE, et al. Nature. 2019 Jan;565(7740):495-499. doi: 10.1038/s41586-018-0846-z. Epub 2019 Jan 9. Nature. 2019. PMID: 30626970 Free PMC article.
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