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Positive-strand RNA viruses-a Keystone Symposia report.
Cable J, Denison MR, Kielian M, Jackson WT, Bartenschlager R, Ahola T, Mukhopadhyay S, Fremont DH, Kuhn RJ, Shannon A, Frazier MN, Yuen KY, Coyne CB, Wolthers KC, Ming GL, Guenther CS, Moshiri J, Best SM, Schoggins JW, Jurado KA, Ebel GD, Schäfer A, Ng LFP, Kikkert M, Sette A, Harris E, Wing PAC, Eggenberger J, Krishnamurthy SR, Mah MG, Meganck RM, Chung D, Maurer-Stroh S, Andino R, Korber B, Perlman S, Shi PY, Bárcena M, Aicher SM, Vu MN, Kenney DJ, Lindenbach BD, Nishida Y, Rénia L, Williams EP. Cable J, et al. Among authors: meganck rm. Ann N Y Acad Sci. 2023 Mar;1521(1):46-66. doi: 10.1111/nyas.14957. Epub 2023 Jan 25. Ann N Y Acad Sci. 2023. PMID: 36697369 Free PMC article.
Host range, transmissibility and antigenicity of a pangolin coronavirus.
Hou YJ, Chiba S, Leist SR, Meganck RM, Martinez DR, Schäfer A, Catanzaro NJ, Sontake V, West A, Edwards CE, Yount B, Lee RE, Gallant SC, Zost SJ, Powers J, Adams L, Kong EF, Mattocks M, Tata A, Randell SH, Tata PR, Halfmann P, Crowe JE Jr, Kawaoka Y, Baric RS. Hou YJ, et al. Among authors: meganck rm. Nat Microbiol. 2023 Oct;8(10):1820-1833. doi: 10.1038/s41564-023-01476-x. Epub 2023 Sep 25. Nat Microbiol. 2023. PMID: 37749254 Free PMC article.
Genomewide CRISPR knockout screen identified PLAC8 as an essential factor for SADS-CoVs infection.
Tse LV, Meganck RM, Araba KC, Yount BL, Shaffer KM, Hou YJ, Munt JE, Adams LE, Wykoff JA, Morowitz JM, Dong S, Magness ST, Marzluff WF, Gonzalez LM, Ehre C, Baric RS. Tse LV, et al. Among authors: meganck rm. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2118126119. doi: 10.1073/pnas.2118126119. Epub 2022 Apr 27. Proc Natl Acad Sci U S A. 2022. PMID: 35476513 Free PMC article.
A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.
Tse LV, Hou YJ, McFadden E, Lee RE, Scobey TD, Leist SR, Martinez DR, Meganck RM, Schäfer A, Yount BL, Mascenik T, Powers JM, Randell SH, Zhang Y, Wang L, Mascola J, McLellan JS, Baric RS. Tse LV, et al. Among authors: meganck rm. Sci Transl Med. 2023 Sep 27;15(715):eadg5567. doi: 10.1126/scitranslmed.adg5567. Epub 2023 Sep 27. Sci Transl Med. 2023. PMID: 37756379
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice.
Schäfer A, Martinez DR, Won JJ, Meganck RM, Moreira FR, Brown AJ, Gully KL, Zweigart MR, Conrad WS, May SR, Dong S, Kalla R, Chun K, Du Pont V, Babusis D, Tang J, Murakami E, Subramanian R, Barrett KT, Bleier BJ, Bannister R, Feng JY, Bilello JP, Cihlar T, Mackman RL, Montgomery SA, Baric RS, Sheahan TP. Schäfer A, et al. Among authors: meganck rm. Sci Transl Med. 2022 May 4;14(643):eabm3410. doi: 10.1126/scitranslmed.abm3410. Epub 2022 May 4. Sci Transl Med. 2022. PMID: 35315683 Free PMC article.
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination.
Munt JE, Henein S, Adams C, Young E, Hou YJ, Conrad H, Zhu D, Dong S, Kose N, Yount B, Meganck RM, Tse LPV, Kuan G, Balmaseda A, Ricciardi MJ, Watkins DI, Crowe JE Jr, Harris E, DeSilva AM, Baric RS. Munt JE, et al. Among authors: meganck rm. Cell Host Microbe. 2023 Nov 8;31(11):1850-1865.e5. doi: 10.1016/j.chom.2023.10.004. Epub 2023 Oct 30. Cell Host Microbe. 2023. PMID: 37909048
Inducing circular RNA formation using the CRISPR endoribonuclease Csy4.
Borchardt EK, Meganck RM, Vincent HA, Ball CB, Ramos SBV, Moorman NJ, Marzluff WF, Asokan A. Borchardt EK, et al. Among authors: meganck rm. RNA. 2017 May;23(5):619-627. doi: 10.1261/rna.056838.116. Epub 2017 Feb 21. RNA. 2017. PMID: 28223408 Free PMC article.
27 results