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Positive-strand RNA viruses-a Keystone Symposia report.
Cable J, Denison MR, Kielian M, Jackson WT, Bartenschlager R, Ahola T, Mukhopadhyay S, Fremont DH, Kuhn RJ, Shannon A, Frazier MN, Yuen KY, Coyne CB, Wolthers KC, Ming GL, Guenther CS, Moshiri J, Best SM, Schoggins JW, Jurado KA, Ebel GD, Schäfer A, Ng LFP, Kikkert M, Sette A, Harris E, Wing PAC, Eggenberger J, Krishnamurthy SR, Mah MG, Meganck RM, Chung D, Maurer-Stroh S, Andino R, Korber B, Perlman S, Shi PY, Bárcena M, Aicher SM, Vu MN, Kenney DJ, Lindenbach BD, Nishida Y, Rénia L, Williams EP. Cable J, et al. Among authors: shannon a. Ann N Y Acad Sci. 2023 Mar;1521(1):46-66. doi: 10.1111/nyas.14957. Epub 2023 Jan 25. Ann N Y Acad Sci. 2023. PMID: 36697369 Free PMC article.
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective.
Seifert M, Bera SC, van Nies P, Kirchdoerfer RN, Shannon A, Le TT, Meng X, Xia H, Wood JM, Harris LD, Papini FS, Arnold JJ, Almo S, Grove TL, Shi PY, Xiang Y, Canard B, Depken M, Cameron CE, Dulin D. Seifert M, et al. Among authors: shannon a. Elife. 2021 Oct 7;10:e70968. doi: 10.7554/eLife.70968. Elife. 2021. PMID: 34617885 Free PMC article.
Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase.
Shannon A, Selisko B, Le N, Huchting J, Touret F, Piorkowski G, Fattorini V, Ferron F, Decroly E, Meier C, Coutard B, Peersen O, Canard B. Shannon A, et al. bioRxiv [Preprint]. 2020 May 15:2020.05.15.098731. doi: 10.1101/2020.05.15.098731. bioRxiv. 2020. PMID: 32511380 Free PMC article. Preprint.
AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5.
Feracci M, Eydoux C, Fattorini V, Lo Bello L, Gauffre P, Selisko B, Sutto-Ortiz P, Shannon A, Xia H, Shi PY, Noel M, Debart F, Vasseur JJ, Good S, Lin K, Moussa A, Sommadossi JP, Chazot A, Alvarez K, Guillemot JC, Decroly E, Ferron F, Canard B. Feracci M, et al. Among authors: shannon a. Antiviral Res. 2023 Apr;212:105574. doi: 10.1016/j.antiviral.2023.105574. Epub 2023 Mar 9. Antiviral Res. 2023. PMID: 36905944
Drugs against SARS-CoV-2: What do we know about their mode of action?
Valle C, Martin B, Touret F, Shannon A, Canard B, Guillemot JC, Coutard B, Decroly E. Valle C, et al. Among authors: shannon a. Rev Med Virol. 2020 Nov;30(6):1-10. doi: 10.1002/rmv.2143. Epub 2020 Aug 11. Rev Med Virol. 2020. PMID: 32779326 Free PMC article. Review.
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Shannon A, Fattorini V, Sama B, Selisko B, Feracci M, Falcou C, Gauffre P, El Kazzi P, Delpal A, Decroly E, Alvarez K, Eydoux C, Guillemot JC, Moussa A, Good SS, La Colla P, Lin K, Sommadossi JP, Zhu Y, Yan X, Shi H, Ferron F, Canard B. Shannon A, et al. Nat Commun. 2022 Feb 2;13(1):621. doi: 10.1038/s41467-022-28113-1. Nat Commun. 2022. PMID: 35110538 Free PMC article.
310 results