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In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice.
Bouffi C, Wikenheiser-Brokamp KA, Chaturvedi P, Sundaram N, Goddard GR, Wunderlich M, Brown NE, Staab JF, Latanich R, Zachos NC, Holloway EM, Mahe MM, Poling HM, Vales S, Fisher GW, Spence JR, Mulloy JC, Zorn AM, Wells JM, Helmrath MA. Bouffi C, et al. Among authors: helmrath ma. Nat Biotechnol. 2023 Jun;41(6):824-831. doi: 10.1038/s41587-022-01558-x. Epub 2023 Jan 26. Nat Biotechnol. 2023. PMID: 36702898 Free PMC article.
Intestinal stem cells remain viable after prolonged tissue storage.
Fuller MK, Faulk DM, Sundaram N, Mahe MM, Stout KM, von Furstenberg RJ, Smith BJ, McNaughton KK, Shroyer NF, Helmrath MA, Henning SJ. Fuller MK, et al. Among authors: helmrath ma. Cell Tissue Res. 2013 Nov;354(2):441-50. doi: 10.1007/s00441-013-1674-y. Epub 2013 Jul 3. Cell Tissue Res. 2013. PMID: 23820734 Free PMC article.
Establishment of Gastrointestinal Epithelial Organoids.
Mahe MM, Aihara E, Schumacher MA, Zavros Y, Montrose MH, Helmrath MA, Sato T, Shroyer NF. Mahe MM, et al. Among authors: helmrath ma. Curr Protoc Mouse Biol. 2013 Dec 19;3(4):217-40. doi: 10.1002/9780470942390.mo130179. Curr Protoc Mouse Biol. 2013. PMID: 25105065 Free PMC article.
An in vivo model of human small intestine using pluripotent stem cells.
Watson CL, Mahe MM, Múnera J, Howell JC, Sundaram N, Poling HM, Schweitzer JI, Vallance JE, Mayhew CN, Sun Y, Grabowski G, Finkbeiner SR, Spence JR, Shroyer NF, Wells JM, Helmrath MA. Watson CL, et al. Among authors: helmrath ma. Nat Med. 2014 Nov;20(11):1310-4. doi: 10.1038/nm.3737. Epub 2014 Oct 19. Nat Med. 2014. PMID: 25326803 Free PMC article.
Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo.
Finkbeiner SR, Hill DR, Altheim CH, Dedhia PH, Taylor MJ, Tsai YH, Chin AM, Mahe MM, Watson CL, Freeman JJ, Nattiv R, Thomson M, Klein OD, Shroyer NF, Helmrath MA, Teitelbaum DH, Dempsey PJ, Spence JR. Finkbeiner SR, et al. Among authors: helmrath ma. Stem Cell Reports. 2015 Jun 3;4(6):1140-55. doi: 10.1016/j.stemcr.2015.04.010. Online ahead of print. Stem Cell Reports. 2015. PMID: 26050928 Free PMC article.
Drug-induced secretory diarrhea: A role for CFTR.
Moon C, Zhang W, Sundaram N, Yarlagadda S, Reddy VS, Arora K, Helmrath MA, Naren AP. Moon C, et al. Among authors: helmrath ma. Pharmacol Res. 2015 Dec;102:107-112. doi: 10.1016/j.phrs.2015.08.024. Epub 2015 Sep 30. Pharmacol Res. 2015. PMID: 26429773 Free PMC article. Review.
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.
Workman MJ, Mahe MM, Trisno S, Poling HM, Watson CL, Sundaram N, Chang CF, Schiesser J, Aubert P, Stanley EG, Elefanty AG, Miyaoka Y, Mandegar MA, Conklin BR, Neunlist M, Brugmann SA, Helmrath MA, Wells JM. Workman MJ, et al. Among authors: helmrath ma. Nat Med. 2017 Jan;23(1):49-59. doi: 10.1038/nm.4233. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869805 Free PMC article.
152 results