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Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue.
Dhavale DD, Barclay AM, Borcik CG, Basore K, Berthold DA, Gordon IR, Liu J, Milchberg MH, O'Shea JY, Rau MJ, Smith Z, Sen S, Summers B, Smith J, Warmuth OA, Perrin RJ, Perlmutter JS, Chen Q, Fitzpatrick JAJ, Schwieters CD, Tajkhorshid E, Rienstra CM, Kotzbauer PT. Dhavale DD, et al. Among authors: fitzpatrick jaj. Nat Commun. 2024 Mar 29;15(1):2750. doi: 10.1038/s41467-024-46832-5. Nat Commun. 2024. PMID: 38553463 Free PMC article.
Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin Deficiency.
Li J, Moretti F, Hidvegi T, Sviben S, Fitzpatrick JAJ, Sundaramoorthi H, Pak SC, Silverman GA, Knapp B, Filipuzzi I, Alford J, Reece-Hoyes J, Nigsch F, Murphy LO, Nyfeler B, Perlmutter DH. Li J, et al. Among authors: fitzpatrick jaj. Cell Mol Gastroenterol Hepatol. 2024;17(6):1007-1024. doi: 10.1016/j.jcmgh.2024.02.006. Epub 2024 Feb 7. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38336172 Free PMC article.
Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes.
Deveryshetty J, Chadda R, Mattice JR, Karunakaran S, Rau MJ, Basore K, Pokhrel N, Englander N, Fitzpatrick JAJ, Bothner B, Antony E. Deveryshetty J, et al. Among authors: fitzpatrick jaj. Nat Commun. 2023 Oct 5;14(1):6215. doi: 10.1038/s41467-023-41993-1. Nat Commun. 2023. PMID: 37798272 Free PMC article.
Poly-basic peptides and polymers as new drug candidate against Plasmodium falciparum.
Sivakumar R, Floyd K, Jessey E, Kim JK, Bayguinov PO, Fitzpatrick JAJ, Goldfrab D, Jovanovic M, Tripathi A, Djuranovic S, Pavlovic-Djuranovic S. Sivakumar R, et al. Among authors: fitzpatrick jaj. bioRxiv [Preprint]. 2023 Sep 16:2023.09.16.558069. doi: 10.1101/2023.09.16.558069. bioRxiv. 2023. PMID: 37745508 Free PMC article. Preprint.
Endogenous recapitulation of Alzheimer's disease neuropathology through human 3D direct neuronal reprogramming.
Sun Z, Kwon JS, Ren Y, Chen S, Cates K, Lu X, Walker CK, Karahan H, Sviben S, Fitzpatrick JAJ, Valdez C, Houlden H, Karch CM, Bateman RJ, Sato C, Mennerick SJ, Diamond MI, Kim J, Tanzi RE, Holtzman DM, Yoo AS. Sun Z, et al. Among authors: fitzpatrick jaj. bioRxiv [Preprint]. 2023 May 25:2023.05.24.542155. doi: 10.1101/2023.05.24.542155. bioRxiv. 2023. PMID: 37292658 Free PMC article. Preprint.
Structural and functional analysis of human pannexin 2 channel.
He Z, Zhao Y, Rau MJ, Fitzpatrick JAJ, Sah R, Hu H, Yuan P. He Z, et al. Among authors: fitzpatrick jaj. Nat Commun. 2023 Mar 27;14(1):1712. doi: 10.1038/s41467-023-37413-z. Nat Commun. 2023. PMID: 36973289 Free PMC article.
Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination.
Hou J, Zhou Y, Cai Z, Terekhova M, Swain A, Andhey PS, Guimaraes RM, Ulezko Antonova A, Qiu T, Sviben S, Strout G, Fitzpatrick JAJ, Chen Y, Gilfillan S, Kim DH, Van Dyken SJ, Artyomov MN, Colonna M. Hou J, et al. Among authors: fitzpatrick jaj. Cell Rep. 2023 Apr 25;42(4):112293. doi: 10.1016/j.celrep.2023.112293. Epub 2023 Mar 21. Cell Rep. 2023. PMID: 36952346 Free PMC article.
86 results