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The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon.
Kong L, Pokatayev V, Lefkovith A, Carter GT, Creasey EA, Krishna C, Subramanian S, Kochar B, Ashenberg O, Lau H, Ananthakrishnan AN, Graham DB, Deguine J, Xavier RJ. Kong L, et al. Among authors: creasey ea. Immunity. 2023 Feb 14;56(2):444-458.e5. doi: 10.1016/j.immuni.2023.01.002. Epub 2023 Jan 30. Immunity. 2023. PMID: 36720220 Free PMC article.
The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon.
Kong L, Pokatayev V, Lefkovith A, Carter GT, Creasey EA, Krishna C, Subramanian S, Kochar B, Ashenberg O, Lau H, Ananthakrishnan AN, Graham DB, Deguine J, Xavier RJ. Kong L, et al. Among authors: creasey ea. Immunity. 2023 Dec 12;56(12):2855. doi: 10.1016/j.immuni.2023.10.017. Immunity. 2023. PMID: 38091954 No abstract available.
Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses.
Brandt M, Cao Z, Krishna C, Reedy JL, Gu X, Dutko RA, Oliver BA, Tusi BK, Park J, Richey L, Segerstolpe Å, Litwiler S, Creasey EA, Carey KL, Vyas JM, Graham DB, Xavier RJ. Brandt M, et al. Among authors: creasey ea. Cell Rep. 2024 Mar 26;43(3):113944. doi: 10.1016/j.celrep.2024.113944. Epub 2024 Mar 13. Cell Rep. 2024. PMID: 38489265 Free PMC article.
Genetic vulnerability to Crohn's disease reveals a spatially resolved epithelial restitution program.
Nakata T, Li C, Mayassi T, Lin H, Ghosh K, Segerstolpe Å, Diamond EL, Herbst P, Biancalani T, Gaddam S, Parkar S, Lu Z, Jaiswal A, Li B, Creasey EA, Lefkovith A, Daly MJ, Graham DB, Xavier RJ. Nakata T, et al. Among authors: creasey ea. Sci Transl Med. 2023 Oct 25;15(719):eadg5252. doi: 10.1126/scitranslmed.adg5252. Epub 2023 Oct 25. Sci Transl Med. 2023. PMID: 37878672 Free PMC article.
The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain.
Mealer RG, Williams SE, Noel M, Yang B, D'Souza AK, Nakata T, Graham DB, Creasey EA, Cetinbas M, Sadreyev RI, Scolnick EM, Woo CM, Smoller JW, Xavier RJ, Cummings RD. Mealer RG, et al. Among authors: creasey ea. Mol Psychiatry. 2022 Mar;27(3):1405-1415. doi: 10.1038/s41380-022-01490-1. Epub 2022 Mar 8. Mol Psychiatry. 2022. PMID: 35260802 Free PMC article.
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Smillie CS, Biton M, Ordovas-Montanes J, Sullivan KM, Burgin G, Graham DB, Herbst RH, Rogel N, Slyper M, Waldman J, Sud M, Andrews E, Velonias G, Haber AL, Jagadeesh K, Vickovic S, Yao J, Stevens C, Dionne D, Nguyen LT, Villani AC, Hofree M, Creasey EA, Huang H, Rozenblatt-Rosen O, Garber JJ, Khalili H, Desch AN, Daly MJ, Ananthakrishnan AN, Shalek AK, Xavier RJ, Regev A. Smillie CS, et al. Among authors: creasey ea. Cell. 2019 Jul 25;178(3):714-730.e22. doi: 10.1016/j.cell.2019.06.029. Cell. 2019. PMID: 31348891 Free PMC article.
18 results