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Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer's disease and aging.
Paudel B, Jeong SY, Martinez CP, Rickman A, Haluck-Kangas A, Bartom ET, Fredriksen K, Affaneh A, Kessler JA, Mazzulli JR, Murmann AE, Rogalski E, Geula C, Ferreira A, Heckmann BL, Green DR, Sadleir KR, Vassar R, Peter ME. Paudel B, et al. Among authors: heckmann bl. Nat Commun. 2024 Jan 18;15(1):264. doi: 10.1038/s41467-023-44465-8. Nat Commun. 2024. PMID: 38238311 Free PMC article.
Anti-amyloid: An antibody to cure Alzheimer's or an attitude.
Osborne OM, Naranjo O, Heckmann BL, Dykxhoorn D, Toborek M. Osborne OM, et al. Among authors: heckmann bl. iScience. 2023 Jul 24;26(8):107461. doi: 10.1016/j.isci.2023.107461. eCollection 2023 Aug 18. iScience. 2023. PMID: 37588168 Free PMC article. Review.
Assessing Color-Blind Racism in Nursing Students.
Ramsay-Seaner K, Letcher A, Isaacson MJ, Fenster K, Heckmann B. Ramsay-Seaner K, et al. Among authors: heckmann b. Nurs Educ Perspect. 2023 May-Jun 01;44(3):172-174. doi: 10.1097/01.NEP.0000000000001045. Epub 2022 Sep 6. Nurs Educ Perspect. 2023. PMID: 36731085
Autotaxin facilitates selective LPA receptor signaling.
Salgado-Polo F, Borza R, Matsoukas MT, Marsais F, Jagerschmidt C, Waeckel L, Moolenaar WH, Ford P, Heckmann B, Perrakis A. Salgado-Polo F, et al. Among authors: heckmann b. Cell Chem Biol. 2023 Jan 19;30(1):69-84.e14. doi: 10.1016/j.chembiol.2022.12.006. Epub 2023 Jan 13. Cell Chem Biol. 2023. PMID: 36640760 Free article.
Beyond autophagy: LC3-associated phagocytosis and endocytosis.
Peña-Martinez C, Rickman AD, Heckmann BL. Peña-Martinez C, et al. Among authors: heckmann bl. Sci Adv. 2022 Oct 28;8(43):eabn1702. doi: 10.1126/sciadv.abn1702. Epub 2022 Oct 26. Sci Adv. 2022. PMID: 36288309 Free PMC article. Review.
Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases.
Mammoliti O, Jansen K, El Bkassiny S, Palisse A, Triballeau N, Bucher D, Allart B, Jaunet A, Tricarico G, De Wachter M, Menet C, Blanc J, Letfus V, Rupčić R, Šmehil M, Poljak T, Coornaert B, Sonck K, Duys I, Waeckel L, Lecru L, Marsais F, Jagerschmidt C, Auberval M, Pujuguet P, Oste L, Borgonovi M, Wakselman E, Christophe T, Houvenaghel N, Jans M, Heckmann B, Sanière L, Brys R. Mammoliti O, et al. Among authors: heckmann b. J Med Chem. 2021 Oct 14;64(19):14557-14586. doi: 10.1021/acs.jmedchem.1c01066. Epub 2021 Sep 28. J Med Chem. 2021. PMID: 34581584
Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis.
Mammoliti O, Palisse A, Joannesse C, El Bkassiny S, Allart B, Jaunet A, Menet C, Coornaert B, Sonck K, Duys I, Clément-Lacroix P, Oste L, Borgonovi M, Wakselman E, Christophe T, Houvenaghel N, Jans M, Heckmann B, Sanière L, Brys R. Mammoliti O, et al. Among authors: heckmann b. J Med Chem. 2021 May 13;64(9):6037-6058. doi: 10.1021/acs.jmedchem.1c00138. Epub 2021 May 3. J Med Chem. 2021. PMID: 33939425
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