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WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer RE, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, Mulkearns-Hubert EE, Johnson S, Alvarado J, Rich JN, Holland EC, Paddison PJ, Patel AP, Stauffer SR, Hubert CG, Lathia JD. Mitchell K, et al. Among authors: hubert cg. Genes Dev. 2023 Feb 1;37(3-4):86-102. doi: 10.1101/gad.349803.122. Epub 2023 Feb 2. Genes Dev. 2023. PMID: 36732025 Free PMC article.
Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells.
Ding Y, Hubert CG, Herman J, Corrin P, Toledo CM, Skutt-Kakaria K, Vazquez J, Basom R, Zhang B, Risler JK, Pollard SM, Nam DH, Delrow JJ, Zhu J, Lee J, DeLuca J, Olson JM, Paddison PJ. Ding Y, et al. Among authors: hubert cg. Cancer Discov. 2013 Feb;3(2):198-211. doi: 10.1158/2159-8290.CD-12-0353. Epub 2012 Nov 15. Cancer Discov. 2013. PMID: 23154965 Free PMC article.
CDC20 maintains tumor initiating cells.
Xie Q, Wu Q, Mack SC, Yang K, Kim L, Hubert CG, Flavahan WA, Chu C, Bao S, Rich JN. Xie Q, et al. Among authors: hubert cg. Oncotarget. 2015 May 30;6(15):13241-54. doi: 10.18632/oncotarget.3676. Oncotarget. 2015. PMID: 25938542 Free PMC article.
Differential connexin function enhances self-renewal in glioblastoma.
Hitomi M, Deleyrolle LP, Mulkearns-Hubert EE, Jarrar A, Li M, Sinyuk M, Otvos B, Brunet S, Flavahan WA, Hubert CG, Goan W, Hale JS, Alvarado AG, Zhang A, Rohaus M, Oli M, Vedam-Mai V, Fortin JM, Futch HS, Griffith B, Wu Q, Xia CH, Gong X, Ahluwalia MS, Rich JN, Reynolds BA, Lathia JD. Hitomi M, et al. Among authors: hubert cg. Cell Rep. 2015 May 19;11(7):1031-42. doi: 10.1016/j.celrep.2015.04.021. Epub 2015 May 7. Cell Rep. 2015. PMID: 25959821 Free PMC article.
Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells.
Schonberg DL, Miller TE, Wu Q, Flavahan WA, Das NK, Hale JS, Hubert CG, Mack SC, Jarrar AM, Karl RT, Rosager AM, Nixon AM, Tesar PJ, Hamerlik P, Kristensen BW, Horbinski C, Connor JR, Fox PL, Lathia JD, Rich JN. Schonberg DL, et al. Among authors: hubert cg. Cancer Cell. 2015 Oct 12;28(4):441-455. doi: 10.1016/j.ccell.2015.09.002. Cancer Cell. 2015. PMID: 26461092 Free PMC article.
An epigenetic gateway to brain tumor cell identity.
Mack SC, Hubert CG, Miller TE, Taylor MD, Rich JN. Mack SC, et al. Among authors: hubert cg. Nat Neurosci. 2016 Jan;19(1):10-9. doi: 10.1038/nn.4190. Nat Neurosci. 2016. PMID: 26713744 Free PMC article. Review.
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma.
Wang X, Yang K, Xie Q, Wu Q, Mack SC, Shi Y, Kim LJY, Prager BC, Flavahan WA, Liu X, Singer M, Hubert CG, Miller TE, Zhou W, Huang Z, Fang X, Regev A, Suvà ML, Hwang TH, Locasale JW, Bao S, Rich JN. Wang X, et al. Among authors: hubert cg. Nat Neurosci. 2017 May;20(5):661-673. doi: 10.1038/nn.4537. Epub 2017 Mar 27. Nat Neurosci. 2017. PMID: 28346452 Free PMC article.
37 results