Stauffer SR - Search Results

1

WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.

Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer RE, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, Mulkearns-Hubert EE, Johnson S, Alvarado J, Rich JN, Holland EC, Paddison PJ, Patel AP, Stauffer SR, Hubert CG, Lathia JD. Mitchell K, et al. Among authors: stauffer sr. Genes Dev. 2023 Feb 1;37(3-4):86-102. doi: 10.1101/gad.349803.122. Epub 2023 Feb 2. Genes Dev. 2023. PMID: 36732025 Free PMC article.

2

BMX controls 3βHSD1 and sex steroid biosynthesis in cancer.

Li X, Berk M, Goins C, Alyamani M, Chung YM, Wang C, Patel M, Rathi N, Zhu Z, Willard B, Stauffer S, Klein E, Sharifi N. Li X, et al. J Clin Invest. 2023 Jan 17;133(2):e163498. doi: 10.1172/JCI163498. J Clin Invest. 2023. PMID: 36647826 Free PMC article.

3

Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication.

Serman T, Chiang C, Liu G, Sayyad Z, Pandey S, Volcic M, Lee H, Muppala S, Acharya D, Goins C, Stauffer SR, Sparrer KMJ, Gack MU. Serman T, et al. Among authors: stauffer sr. Cell Host Microbe. 2023 Aug 9;31(8):1317-1330.e10. doi: 10.1016/j.chom.2023.06.013. Epub 2023 Jul 20. Cell Host Microbe. 2023. PMID: 37478852

4

A TOX-ic axis of epigenetic stem cell maintenance and chemoresistance in colon cancer.

Hubert CG, Stauffer SR, Lathia JD. Hubert CG, et al. Among authors: stauffer sr. PLoS Biol. 2023 Sep 15;21(9):e3002295. doi: 10.1371/journal.pbio.3002295. eCollection 2023 Sep. PLoS Biol. 2023. PMID: 37713380 Free PMC article.

5

Leveraging Hot Spots of TEAD-Coregulator Interactions in the Design of Direct Small Molecule Protein-Protein Interaction Disruptors Targeting Hippo Pathway Signaling.

Zhao B, Pobbati AV, Rubin BP, Stauffer S. Zhao B, et al. Pharmaceuticals (Basel). 2023 Apr 13;16(4):583. doi: 10.3390/ph16040583. Pharmaceuticals (Basel). 2023. PMID: 37111340 Free PMC article. Review.

6

Characterization of a novel positive allosteric modulator of the α_1A-Adrenergic receptor.

Papay RS, Macdonald JD, Stauffer SR, Perez DM. Papay RS, et al. Among authors: stauffer sr. Curr Res Pharmacol Drug Discov. 2022 Dec 2;4:100142. doi: 10.1016/j.crphar.2022.100142. eCollection 2023. Curr Res Pharmacol Drug Discov. 2022. PMID: 36544813 Free PMC article.

7

A PAM of the α_1A-Adrenergic receptor rescues biomarker, long-term potentiation, and cognitive deficits in Alzheimer's disease mouse models without effects on blood pressure.

Papay RS, Stauffer SR, Perez DM. Papay RS, et al. Among authors: stauffer sr. Curr Res Pharmacol Drug Discov. 2023 Jun 27;5:100160. doi: 10.1016/j.crphar.2023.100160. eCollection 2023. Curr Res Pharmacol Drug Discov. 2023. PMID: 37448695 Free PMC article.

8

Author Correction: Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease.

Fang J, Zhang P, Zhou Y, Chiang CW, Tan J, Hou Y, Stauffer S, Li L, Pieper AA, Cummings J, Cheng F. Fang J, et al. Nat Aging. 2023 Jul;3(7):908. doi: 10.1038/s43587-023-00396-z. Nat Aging. 2023. PMID: 37118557 No abstract available.

9

Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase.

Maw JJ, Coker JA, Arya T, Goins CM, Sonawane D, Han SH, Rees MG, Ronan MM, Roth JA, Wang NS, Heemers HV, Macdonald JD, Stauffer SR. Maw JJ, et al. Among authors: stauffer sr. J Med Chem. 2024 Feb 22;67(4):2631-2666. doi: 10.1021/acs.jmedchem.3c01807. Epub 2024 Feb 8. J Med Chem. 2024. PMID: 38330278

10

Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase.

Rawat C, Ben-Salem S, Singh N, Chauhan G, Rabljenovic A, Vaghela V, Venkadakrishnan VB, Macdonald JD, Dahiya UR, Ghanem Y, Bachour S, Su Y, DePriest AD, Lee S, Muldong M, Kim HT, Kumari S, Valenzuela MM, Zhang D, Hu Q, Cortes Gomez E, Dehm SM, Zoubeidi A, Jamieson CAM, Nicolas M, McKenney J, Willard B, Klein EA, Magi-Galluzzi C, Stauffer SR, Liu S, Heemers HV. Rawat C, et al. Among authors: stauffer sr. Cancer Res. 2023 Dec 15;83(24):4142-4160. doi: 10.1158/0008-5472.CAN-23-0883. Cancer Res. 2023. PMID: 37801613

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