Murphy SE - Search Results

1

Quantitation of Ten Urinary Nicotine Metabolites, Including 4-Hydroxy-4-(3-pyridyl) Butanoic Acid, a Product of Nicotine 2'-Oxidation, and CYP2A6 Activity in Japanese Americans, Native Hawaiians, and Whites.

von Weymarn LB, Lu X, Thomson NM, LeMarchand L, Park SL, Murphy SE. von Weymarn LB, et al. Among authors: murphy se. Chem Res Toxicol. 2023 Feb 20;36(2):313-321. doi: 10.1021/acs.chemrestox.2c00413. Epub 2023 Feb 3. Chem Res Toxicol. 2023. PMID: 36735658 Free PMC article.

2

Characterization of multiple products of cytochrome P450 2A6-catalyzed cotinine metabolism.

Murphy SE, Johnson LM, Pullo DA. Murphy SE, et al. Chem Res Toxicol. 1999 Jul;12(7):639-45. doi: 10.1021/tx990015e. Chem Res Toxicol. 1999. PMID: 10409404

3

N-Nitrosobenzylmethylamine hydroxylation and coumarin 7-hydroxylation: catalysis by rat esophageal microsomes and cytochrome P450 2A3 and 2A6 enzymes.

von Weymarn LB, Felicia ND, Ding X, Murphy SE. von Weymarn LB, et al. Among authors: murphy se. Chem Res Toxicol. 1999 Dec;12(12):1254-61. doi: 10.1021/tx990128y. Chem Res Toxicol. 1999. PMID: 10604876

4

Coumarin metabolism by rat esophageal microsomes and cytochrome P450 2A3.

von Weymarn LB, Murphy SE. von Weymarn LB, et al. Among authors: murphy se. Chem Res Toxicol. 2001 Oct;14(10):1386-92. doi: 10.1021/tx010065v. Chem Res Toxicol. 2001. PMID: 11599930

5

CYP2A13-catalysed coumarin metabolism: comparison with CYP2A5 and CYP2A6.

von Weymarn LB, Murphy SE. von Weymarn LB, et al. Among authors: murphy se. Xenobiotica. 2003 Jan;33(1):73-81. doi: 10.1080/0049825021000022302. Xenobiotica. 2003. PMID: 12519695

6

Preferential metabolic activation of N-nitrosopiperidine as compared to its structural homologue N-nitrosopyrrolidine by rat nasal mucosal microsomes.

Wong HL, Murphy SE, Hecht SS. Wong HL, et al. Among authors: murphy se. Chem Res Toxicol. 2003 Oct;16(10):1298-305. doi: 10.1021/tx0340495. Chem Res Toxicol. 2003. PMID: 14565771

7

N-glucuronidation of trans-3'-hydroxycotinine by human liver microsomes.

Kuehl GE, Murphy SE. Kuehl GE, et al. Among authors: murphy se. Chem Res Toxicol. 2003 Dec;16(12):1502-6. doi: 10.1021/tx034173o. Chem Res Toxicol. 2003. PMID: 14680362

8

Metabolic activation of the tobacco carcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone by cytochrome P450 2A13 in human fetal nasal microsomes.

Wong HL, Zhang X, Zhang QY, Gu J, Ding X, Hecht SS, Murphy SE. Wong HL, et al. Among authors: murphy se. Chem Res Toxicol. 2005 Jun;18(6):913-8. doi: 10.1021/tx0500777. Chem Res Toxicol. 2005. PMID: 15962925

9

Inactivation of CYP2A6 and CYP2A13 during nicotine metabolism.

von Weymarn LB, Brown KM, Murphy SE. von Weymarn LB, et al. Among authors: murphy se. J Pharmacol Exp Ther. 2006 Jan;316(1):295-303. doi: 10.1124/jpet.105.091306. Epub 2005 Sep 27. J Pharmacol Exp Ther. 2006. PMID: 16188955

10

Identification of N-(hydroxymethyl) norcotinine as a major product of cytochrome P450 2A6, but not cytochrome P450 2A13-catalyzed cotinine metabolism.

Brown KM, von Weymarn LB, Murphy SE. Brown KM, et al. Among authors: murphy se. Chem Res Toxicol. 2005 Dec;18(12):1792-8. doi: 10.1021/tx0501381. Chem Res Toxicol. 2005. PMID: 16359169

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