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The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux and macrophage-induced rifampicin tolerance.
Lake MA, Adams KN, Nie F, Fowler E, Verma AK, Dei S, Teodori E, Sherman DR, Edelstein PH, Spring DR, Troll M, Ramakrishnan L. Lake MA, et al. Among authors: troll m. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2215512120. doi: 10.1073/pnas.2215512120. Epub 2023 Feb 10. Proc Natl Acad Sci U S A. 2023. PMID: 36763530 Free PMC article.
Gaucher disease protects against tuberculosis.
Fan J, Hale VL, Lelieveld LT, Whitworth LJ, Busch-Nentwich EM, Troll M, Edelstein PH, Cox TM, Roca FJ, Aerts JMFG, Ramakrishnan L. Fan J, et al. Among authors: troll m. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2217673120. doi: 10.1073/pnas.2217673120. Epub 2023 Feb 6. Proc Natl Acad Sci U S A. 2023. PMID: 36745788 Free PMC article.
Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials.
Dawed AY, Mari A, Brown A, McDonald TJ, Li L, Wang S, Hong MG, Sharma S, Robertson NR, Mahajan A, Wang X, Walker M, Gough S, Hart LM', Zhou K, Forgie I, Ruetten H, Pavo I, Bhatnagar P, Jones AG, Pearson ER; DIRECT consortium. Dawed AY, et al. Lancet Diabetes Endocrinol. 2023 Jan;11(1):33-41. doi: 10.1016/S2213-8587(22)00340-0. Lancet Diabetes Endocrinol. 2023. PMID: 36528349 Free article.
Larger gray matter volumes in neuropsychiatric long-COVID syndrome.
Besteher B, Machnik M, Troll M, Toepffer A, Zerekidze A, Rocktäschel T, Heller C, Kikinis Z, Brodoehl S, Finke K, Reuken PA, Opel N, Stallmach A, Gaser C, Walter M. Besteher B, et al. Among authors: troll m. Psychiatry Res. 2022 Nov;317:114836. doi: 10.1016/j.psychres.2022.114836. Epub 2022 Sep 6. Psychiatry Res. 2022. PMID: 36087363 Free PMC article.
Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study.
Tura A, Grespan E, Göbl CS, Koivula RW, Franks PW, Pearson ER, Walker M, Forgie IM, Giordano GN, Pavo I, Ruetten H, Dermitzakis ET, McCarthy MI, Pedersen O, Schwenk JM, Adamski J, De Masi F, Tsirigos KD, Brunak S, Viñuela A, Mahajan A, McDonald TJ, Kokkola T, Vangipurapu J, Cederberg H, Laakso M, Rutters F, Elders PJM, Koopman ADM, Beulens JW, Ridderstråle M, Hansen TH, Allin KH, Hansen T, Vestergaard H, Mari A; IMI DIRECT Consortium. Tura A, et al. Diabetes. 2021 Sep;70(9):2092-2106. doi: 10.2337/db21-0227. Epub 2021 Jul 7. Diabetes. 2021. PMID: 34233929
Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone.
Whitworth LJ, Troll R, Pagán AJ, Roca FJ, Edelstein PH, Troll M, Tobin DM, Phu NH, Bang ND, Thwaites GE, Thuong NTT, Sewell RF, Ramakrishnan L. Whitworth LJ, et al. Among authors: troll m. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2024852118. doi: 10.1073/pnas.2024852118. Proc Natl Acad Sci U S A. 2021. PMID: 33658385 Free PMC article.
Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study.
Bizzotto R, Jennison C, Jones AG, Kurbasic A, Tura A, Kennedy G, Bell JD, Thomas EL, Frost G, Eriksen R, Koivula RW, Brage S, Kaye J, Hattersley AT, Heggie A, McEvoy D, 't Hart LM, Beulens JW, Elders P, Musholt PB, Ridderstråle M, Hansen TH, Allin KH, Hansen T, Vestergaard H, Lundgaard AT, Thomsen HS, De Masi F, Tsirigos KD, Brunak S, Viñuela A, Mahajan A, McDonald TJ, Kokkola T, Forgie IM, Giordano GN, Pavo I, Ruetten H, Dermitzakis E, McCarthy MI, Pedersen O, Schwenk JM, Adamski J, Franks PW, Walker M, Pearson ER, Mari A; IMI DIRECT consortium. Bizzotto R, et al. Diabetes Care. 2021 Feb;44(2):511-518. doi: 10.2337/dc20-1567. Epub 2020 Dec 15. Diabetes Care. 2021. PMID: 33323478
A reference map of potential determinants for the human serum metabolome.
Bar N, Korem T, Weissbrod O, Zeevi D, Rothschild D, Leviatan S, Kosower N, Lotan-Pompan M, Weinberger A, Le Roy CI, Menni C, Visconti A, Falchi M, Spector TD; IMI DIRECT consortium; Adamski J, Franks PW, Pedersen O, Segal E. Bar N, et al. Nature. 2020 Dec;588(7836):135-140. doi: 10.1038/s41586-020-2896-2. Epub 2020 Nov 11. Nature. 2020. PMID: 33177712 Clinical Trial.
Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes.
Huang J, Huth C, Covic M, Troll M, Adam J, Zukunft S, Prehn C, Wang L, Nano J, Scheerer MF, Neschen S, Kastenmüller G, Suhre K, Laxy M, Schliess F, Gieger C, Adamski J, Hrabe de Angelis M, Peters A, Wang-Sattler R. Huang J, et al. Among authors: troll m. Diabetes. 2020 Dec;69(12):2756-2765. doi: 10.2337/db20-0586. Epub 2020 Oct 6. Diabetes. 2020. PMID: 33024004
39 results