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Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang Y, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Kelmer Sacramento E, Shah SI, Nalls MA, Colon-Mercado J, Reyes JF, Ryan VH, Nelson MP, Cook C, Li Z, Screven L, Kwan JY, Shantaraman A, Ping L, Koike Y, Oskarsson B, Staff N, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Rohrer J, Malaspina A, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME. Seddighi S, et al. Among authors: petrucelli l. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.525149. doi: 10.1101/2023.01.23.525149. bioRxiv. 2023. PMID: 36747793 Free PMC article. Updated. Preprint.
TDP-43 in neurodegenerative disorders.
Cook C, Zhang YJ, Xu YF, Dickson DW, Petrucelli L. Cook C, et al. Among authors: petrucelli l. Expert Opin Biol Ther. 2008 Jul;8(7):969-78. doi: 10.1517/14712598.8.7.969. Expert Opin Biol Ther. 2008. PMID: 18549326 Free PMC article. Review.
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity.
Zhang YJ, Xu YF, Cook C, Gendron TF, Roettges P, Link CD, Lin WL, Tong J, Castanedes-Casey M, Ash P, Gass J, Rangachari V, Buratti E, Baralle F, Golde TE, Dickson DW, Petrucelli L. Zhang YJ, et al. Among authors: petrucelli l. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7607-12. doi: 10.1073/pnas.0900688106. Epub 2009 Apr 21. Proc Natl Acad Sci U S A. 2009. PMID: 19383787 Free PMC article.
Aging is not associated with proteasome impairment in UPS reporter mice.
Cook C, Gass J, Dunmore J, Tong J, Taylor J, Eriksen J, McGowan E, Lewis J, Johnston J, Petrucelli L. Cook C, et al. Among authors: petrucelli l. PLoS One. 2009 Jun 11;4(6):e5888. doi: 10.1371/journal.pone.0005888. PLoS One. 2009. PMID: 19517018 Free PMC article.
Progranulin: an emerging target for FTLD therapies.
Gass J, Prudencio M, Stetler C, Petrucelli L. Gass J, et al. Among authors: petrucelli l. Brain Res. 2012 Jun 26;1462:118-28. doi: 10.1016/j.brainres.2012.01.047. Epub 2012 Jan 28. Brain Res. 2012. PMID: 22338605 Free PMC article. Review.
Disruption of protein quality control in Parkinson's disease.
Cook C, Stetler C, Petrucelli L. Cook C, et al. Among authors: petrucelli l. Cold Spring Harb Perspect Med. 2012 May;2(5):a009423. doi: 10.1101/cshperspect.a009423. Cold Spring Harb Perspect Med. 2012. PMID: 22553500 Free PMC article. Review.
Tau triage decisions mediated by the chaperone network.
Cook C, Petrucelli L. Cook C, et al. Among authors: petrucelli l. J Alzheimers Dis. 2013;33 Suppl 1:S145-51. doi: 10.3233/JAD-2012-129008. J Alzheimers Dis. 2013. PMID: 22596270 Review.
324 results