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Piperlongumine conjugates induce targeted protein degradation.
Pei J, Xiao Y, Liu X, Hu W, Sobh A, Yuan Y, Zhou S, Hua N, Mackintosh SG, Zhang X, Basso KB, Kamat M, Yang Q, Licht JD, Zheng G, Zhou D, Lv D. Pei J, et al. Among authors: mackintosh sg. Cell Chem Biol. 2023 Feb 16;30(2):203-213.e17. doi: 10.1016/j.chembiol.2023.01.004. Epub 2023 Feb 6. Cell Chem Biol. 2023. PMID: 36750097 Free PMC article.
Oxidation resistance 1 is a novel senolytic target.
Zhang X, Zhang S, Liu X, Wang Y, Chang J, Zhang X, Mackintosh SG, Tackett AJ, He Y, Lv D, Laberge RM, Campisi J, Wang J, Zheng G, Zhou D. Zhang X, et al. Among authors: mackintosh sg. Aging Cell. 2018 Aug;17(4):e12780. doi: 10.1111/acel.12780. Epub 2018 May 15. Aging Cell. 2018. PMID: 29766639 Free PMC article.
A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells.
Xu C, Meng F, Park KS, Storey AJ, Gong W, Tsai YH, Gibson E, Byrum SD, Li D, Edmondson RD, Mackintosh SG, Vedadi M, Cai L, Tackett AJ, Kaniskan HÜ, Jin J, Wang GG. Xu C, et al. Among authors: mackintosh sg. Cell Chem Biol. 2022 Mar 17;29(3):386-397.e9. doi: 10.1016/j.chembiol.2021.08.004. Epub 2021 Aug 31. Cell Chem Biol. 2022. PMID: 34469831 Free PMC article.
Subchronic Electronic Cigarette Exposures Have Overlapping Protein Biomarkers with Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis.
Scieszka D, Byrum SD, Mackintosh SG, Madison M, Knight J, Campen MJ, Kheradmand F. Scieszka D, et al. Among authors: mackintosh sg. Am J Respir Cell Mol Biol. 2022 Oct;67(4):503-506. doi: 10.1165/rcmb.2021-0482LE. Am J Respir Cell Mol Biol. 2022. PMID: 36178855 Free PMC article. No abstract available.
DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA.
Gao J , Byrd AK , Zybailov BL , Marecki JC , Guderyon MJ , Edwards AD , Chib S , West KL , Waldrip ZJ , Mackintosh SG , Gao Z , Putnam AA , Jankowsky E , Raney KD . Gao J , et al. Among authors: mackintosh sg. Chem Commun (Camb). 2019 Apr 11;55(31):4467-4470. doi: 10.1039/c8cc10091h. Chem Commun (Camb). 2019. PMID: 30855040 Free PMC article.
ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.
Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY. Atanassov BS, et al. Among authors: mackintosh sg. Mol Cell. 2016 May 19;62(4):558-71. doi: 10.1016/j.molcel.2016.03.030. Epub 2016 Apr 28. Mol Cell. 2016. PMID: 27132940 Free PMC article.
Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome.
Byrum SD, Loughran AJ, Beenken KE, Orr LM, Storey AJ, Mackintosh SG, Edmondson RD, Tackett AJ, Smeltzer MS. Byrum SD, et al. Among authors: mackintosh sg. J Proteome Res. 2018 Oct 5;17(10):3384-3395. doi: 10.1021/acs.jproteome.8b00288. Epub 2018 Sep 27. J Proteome Res. 2018. PMID: 30209945 Free PMC article.
90 results