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Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes.
Karczewski KJ, Solomonson M, Chao KR, Goodrich JK, Tiao G, Lu W, Riley-Gillis BM, Tsai EA, Kim HI, Zheng X, Rahimov F, Esmaeeli S, Grundstad AJ, Reppell M, Waring J, Jacob H, Sexton D, Bronson PG, Chen X, Hu X, Goldstein JI, King D, Vittal C, Poterba T, Palmer DS, Churchhouse C, Howrigan DP, Zhou W, Watts NA, Nguyen K, Nguyen H, Mason C, Farnham C, Tolonen C, Gauthier LD, Gupta N, MacArthur DG, Rehm HL, Seed C, Philippakis AA, Daly MJ, Davis JW, Runz H, Miller MR, Neale BM. Karczewski KJ, et al. Among authors: nguyen k, nguyen h. Cell Genom. 2022 Aug 15;2(9):100168. doi: 10.1016/j.xgen.2022.100168. eCollection 2022 Sep 14. Cell Genom. 2022. PMID: 36778668 Free PMC article.
TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.
Parnandi N, Rendo V, Cui G, Botuyan MV, Remisova M, Nguyen H, Drané P, Beroukhim R, Altmeyer M, Mer G, Chowdhury D. Parnandi N, et al. Among authors: nguyen h. Mol Cell. 2021 Jun 17;81(12):2583-2595.e6. doi: 10.1016/j.molcel.2021.03.039. Epub 2021 May 6. Mol Cell. 2021. PMID: 33961797 Free PMC article.
A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma.
Pal S, Kaplan JP, Nguyen H, Stopka SA, Savani MR, Regan MS, Nguyen QD, Jones KL, Moreau LA, Peng J, Dipiazza MG, Perciaccante AJ, Zhu X, Hunsel BR, Liu KX, Alexandrescu S, Drissi R, Filbin MG, McBrayer SK, Agar NYR, Chowdhury D, Haas-Kogan DA. Pal S, et al. Among authors: nguyen qd, nguyen h. Cancer Cell. 2022 Sep 12;40(9):957-972.e10. doi: 10.1016/j.ccell.2022.07.012. Epub 2022 Aug 18. Cancer Cell. 2022. PMID: 35985342 Free PMC article.
CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress.
Li F, Kozono D, Deraska P, Branigan T, Dunn C, Zheng XF, Parmar K, Nguyen H, DeCaprio J, Shapiro GI, Chowdhury D, D'Andrea AD. Li F, et al. Among authors: nguyen h. Mol Cell. 2020 Nov 5;80(3):410-422.e6. doi: 10.1016/j.molcel.2020.10.008. Epub 2020 Oct 26. Mol Cell. 2020. PMID: 33108758 Free PMC article.
Functional profiling of nucleotide Excision repair in breast cancer.
Rajkumar-Calkins AS, Szalat R, Dreze M, Khan I, Frazier Z, Reznichenkov E, Schnorenberg MR, Tsai YF, Nguyen H, Kochupurakkal B, D'Andrea AD, Shapiro GI, Lazaro JB, Mouw KW. Rajkumar-Calkins AS, et al. Among authors: nguyen h. DNA Repair (Amst). 2019 Oct;82:102697. doi: 10.1016/j.dnarep.2019.102697. Epub 2019 Aug 30. DNA Repair (Amst). 2019. PMID: 31499327 Free PMC article.
Heterogeneity and Clonal Evolution of Acquired PARP Inhibitor Resistance in TP53- and BRCA1-Deficient Cells.
Färkkilä A, Rodríguez A, Oikkonen J, Gulhan DC, Nguyen H, Domínguez J, Ramos S, Mills CE, Pérez-Villatoro F, Lazaro JB, Zhou J, Clairmont CS, Moreau LA, Park PJ, Sorger PK, Hautaniemi S, Frias S, D'Andrea AD. Färkkilä A, et al. Among authors: nguyen h. Cancer Res. 2021 May 15;81(10):2774-2787. doi: 10.1158/0008-5472.CAN-20-2912. Epub 2021 Jan 29. Cancer Res. 2021. PMID: 33514515 Free PMC article.
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